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Centeno-Schultz Clinic

We are the home of the world’s most sophisticated clinical and lab research facility for stem cells, platelets, and orthobiologics. Regenexx® was founded at our Broomfield, Colorado location. Our 12,000 foot practice facility has state of the art fluoroscopy and MSK ultrasound procedure rooms, a large, state of the art clean room cell processing area, and a fellowship program where we educate young physicians in interventional orthopedics.

Areas treated

Cervical Spine, Elbow, Foot & Ankle, Hand & Wrist, Hip, Knee, Lumbar Spine, Other Conditions, Shoulder, Thoracic Spine

Schedule a Consultation at Centeno-Schultz Clinic


403 Summit Boulevard
Broomfield, CO 80021

Lone Tree

10465 Park Meadows Drive
Ste 105
Lone Tree, CO 80124

Free Educational Seminar

At-Home Spine Health - Week 2: Lumbar

Join us on Tue, May 26th at 12:00 pm for a free educational seminar. We'll be discussing the Regenexx stem cell and blood platelet procedures offered by Centeno-Schultz Clinic.

Reserve Your Seats

Free Educational Seminar

Maximize Your Stem Cell Treatment! Week 2: Graston

Join us on Thu, May 28th at 12:00 pm for a free educational seminar. We'll be discussing the Regenexx stem cell and blood platelet procedures offered by Centeno-Schultz Clinic.

Reserve Your Seats

Free Educational Seminar

At-Home Spine Health - Week 3: Cervical

Join us on Tue, Jun 2nd at 12:00 pm for a free educational seminar. We'll be discussing the Regenexx stem cell and blood platelet procedures offered by Centeno-Schultz Clinic.

Reserve Your Seats

Free Educational Seminar

Maximize Your Stem Cell Treatment! Week 3: IMS

Join us on Thu, Jun 4th at 12:00 pm for a free educational seminar. We'll be discussing the Regenexx stem cell and blood platelet procedures offered by Centeno-Schultz Clinic.

Reserve Your Seats


Christopher J. Centeno, M.D. is an international expert and specialist in regenerative medicine and the clinical use of mesenchymal stem cells in orthopedics. He is board certified in physical medicine as well as rehabilitation and in pain management through The American Board of Physical Medicine and Rehabilitation.

Dr. Centeno is one of the few physicians in the world with extensive experience in the culture expansion of and clinical use of adult stem cells to treat orthopedic injuries. His clinic incorporates a variety of revolutionary pain management techniques to bring its broad patient base relief and results. Dr. Centeno treats patients from all over the US who travel to Colorado to under-go innovative, non-surgical treatments. Dr. Centeno has chaired multiple international research based conferences. He also maintains an active research based practice, with multiple publications listed in the US National Library of Medicine. Dr. Centeno has also served as editor-in-chief of a medical research journal dedicated to traumatic injury.

He hails from both Florida and New York and currently resides in Boulder, Colorado with his wife and three children.

Areas treated: Cervical Spine, Elbow, Foot & Ankle, Hand & Wrist, Hip, Knee, Lumbar Spine, Other Conditions, Shoulder, Thoracic Spine

Dr. Schultz is an interventional pain management specialist and is double-boarded in both Anesthesiology and Pain Management. He is a member and prior instructor for the Spine Interventional Society (SIS) and holds state licensure in Utah, Colorado and North Carolina. Dr. Schultz trained at the Michael Reese Hospital and Medical Center, Children’s Hospital of Philadelphia, and Bowman Gray School of Medicine and currently serves as Co-Medical Director of The Centeno-Schultz Clinic. He has published numerous works in the field of anesthesiology and regenerative science and brings 20 years of experience to Centeno Schultz Clinic and its patients.

Areas treated: Cervical Spine, Elbow, Foot & Ankle, Hand & Wrist, Hip, Knee, Lumbar Spine, Other Conditions, Shoulder, Thoracic Spine

Dr. Pitts is originally from Chicago, IL but is a medical graduate of Vanderbilt School of Medicine in Nashville, TN. After Vanderbilt he completed residency in Physical Medicine and Rehabilitation (PM&R) at Emory University in Atlanta, GA.  The focus of PM&R is restoration of function and quality of life. In residency he gained much experience in musculoskeletal medicine, rehabilitation, spine and sports medicine along with some regenerative medicine.

He also gained significant experience in fluoroscopically guided spinal procedures and peripheral injections. However, Dr. Pitts wanted to broaden his skills and treatment options beyond the current typical standards of care. Thus, he came to Colorado as a fellow to learn more about regenerative medicine and interventional orthopedics as well as to further develop his skills in fluoroscopic guided procedures, diagnostic ultrasound and interventional ultrasound. He has been involved in research and development of the regenerative procedures and post procedural rehabilitation. He completed his fellowship in 2014 and was excited to stay on as a staff physician. 

Additionally he has interests in nutrition, supplements, and complementary and alternative medicine. He has written and published a nutrition guide; 21st Century Guide to Nutrition and Health.  Dr. Pitts believes in taking a holistic approach to patient care.

He is excited to continue to learn and develop his career around regenerative medicine. Dr. Pitts is board certified in Physical Medicine and Rehabilitation. In his spare time he enjoys all outdoor activities, sports, running, hiking, lifting weights, Crossfit, biking, and traveling with his wife.

Areas treated: Cervical Spine, Elbow, Foot & Ankle, Hand & Wrist, Hip, Knee, Lumbar Spine, Shoulder, Thoracic Spine

Dr. Jason Markle is a south Florida native. He graduated from Nova Southeastern University, earning his degree in Osteopathic Medicine (D.O.). After completing an internship at the Westchester General Hospital in Miami, Dr. Markle completed his residency in Physical Medicine and Rehabilitation (PM&R/ Physiatry) at the University of Alabama at Birmingham (UAB). At UAB, Dr. Markle furthered his training in musculoskeletal medicine, rehabilitation, sports and spine.

Post residency, Dr. Markle was selected to the Interventional Orthopedic Fellowship program at the Centeno-Schultz Clinic. During his fellowship, Dr. Markle gained significant experience in the new field of interventional orthopedics and regenerative medicine, honing his skills in advanced interventional injection techniques into the spine and peripheral joints treating patients with orthobiologics. After his completed fellowship, Dr. Markle accepted a full-time attending physician position at the Centeno-Schultz Clinic, where he both treats patients and trains current Interventional Orthopedics fellows. In addition to working at the Centeno-Schultz Clinic, Dr. Markle is an active member of the Interventional Orthopedic Foundation and serves as a course instructor, where he trains physicians from around the world in advanced interventional orthopedic injection techniques: (

Dr. Markle is an outdoor sports enthusiast. In his free time, he enjoys hiking, snowboarding, rock climbing, mountain biking, Olympic weightlifting and Crossfit, and spending time with his wife and two dogs.

Areas treated: Cervical Spine, Elbow, Foot & Ankle, Hand & Wrist, Hip, Knee, Lumbar Spine, Shoulder, Thoracic Spine

Dr. Hyzy is Board Certified and fellowship trained in Interventional Orthopedics. He is published in the use of Autologous Orthobiologics including platelet derived growth factors and mesenchymal stem cells for orthopedic and spinal conditions. Dr. Hyzy is a Chicago native but moved to Florida in his youth and started his pursuit of medical training. Dr. Hyzy completed residency training at The University of Texas at Austin Dell Medical School in Physical Medicine and Rehabilitation (P.M.R./Physiatry). There, he served as Chief resident and garnered numerous clinical experiences in Physiatry, Surgical and Non-Surgical Orthopedics, Neurosurgery, Interventional Physiatry, Pain Management, Interventional Spine and Regenerative Medicine; which fueled his desire to pursue more training in Interventional Orthopedics and Regenerative Medicine. He was subsequently honored to be chosen as a fellow in Interventional Orthopedics at The Centeno Schultz Clinic.

Dr. Hyzy’s previous role as a personal fitness instructor, an Osteopathic Physician, and a Physiatrist have all aligned in a holistic approach to the treatment of patients with pain, impairments, and dysfunction. He uses these experiences to optimize function and decrease pain with biomechanical evaluation, procedural interventions including diagnostic/interventional ultrasound and fluoroscopically guided procedures. Dr. Hyzy continues to promote the field in patient outcomes and research as well as providing clinical training for other physicians while serving as a clinical instructor for the Interventional Orthopedics Foundation. Dr Hyzy has served on numerous organized medicine associations, provided medical coverage for the annual Austin Marathon and provided pre-participation athletic physicals as a resident physician.

Dr. Hyzy is proud to be an attending physician at The Centeno-Schultz Clinic where he is an integral part of the Interventional Orthopedics fellowship and the progression of regenerative medicine research. His research interests include the use of Orthobiologics (Platelet Rich Plasma, Platelet Lysate, and Mesenchymal Stem Cells) in musculoskeletal medicine, Osteoarthritis, percutaneous ACL repair, axial spinal disorders while participating in new treatment strategies to assist patients.

Outside of Medicine, his interests include exploring the Rocky Mountain active lifestyle, paddle boarding, Mtn. Biking, Yoga, international cuisine and spending time with his family and friends.

Areas treated: Cervical Spine, Elbow, Foot & Ankle, Hand & Wrist, Hip, Knee, Lumbar Spine, Shoulder, Thoracic Spine

Dr. Matthew Lucas is a Denver native. He graduated from Colorado State University with a degree in Health Science/Sports Medicine, where he developed a specific interest in sports injuries and exercise physiology. Dr. Lucas completed medical school at Rocky Vista University in Parker, Colorado, where he gained valuable experience in both surgical and non-surgical orthopedics. He later completed residency training at Stanford University in Physical Medicine and Rehabilitation, where he had the opportunity to work with high level athletes and gain skills in interventional pain management using fluoroscopy and ultrasound for precise image guidance procedures. During his medical training, he spent time volunteering for several international medical missions, organized free resident run musculoskeletal clinics, published peer reviewed literature on discogenic low back pain, lectured extensively on sports injuries and stem cell use in orthopedics, and has presented at an international spine conference.

Dr. Lucas’s research interests include developing new minimally invasive techniques in the treatment of musculoskeletal conditions as well as the use of orthobiologics in tissue repair. He continues to have a passion for teaching and education and remains a guest lecturer for the Stanford department of orthopedics.

Dr. Lucas is currently an Interventional Orthopedics Fellow at the Centeno-Schultz Clinic, where he will further his training in advanced interventional procedures and regenerative orthopedics. He is thrilled to be practicing in his home state of Colorado. Outside of work, he spends his time in the mountains fly fishing and golfing. He is an avid Denver and CSU Rams sports fan.

Dr. Chaz Fausel grew up in the Atlanta, Georgia, area. Being the first in his family to graduate college, Dr. Fausel obtained his Bachelor of Science at the University of Georgia, in Athens. Dr. Fausel was then admitted to the Medical College of Georgia in Augusta, where he obtained his Medical Doctorate. During his time at the Medical College of Georgia, Dr. Fausel was exposed to all areas of western medicine but felt like the traditional medical system was failing the patients that it intended to treat.

Looking for a more holistic approach to caring for patients, he pursued a residency in Physical Medicine & Rehabilitation (PM&R) at Emory University in Atlanta, Georgia. During his residency, Dr. Fausel gained significant exposure to traditional interventional fluoroscopically-guided pain procedures, as well as musculoskeletal regenerative medicine.

Dr. Fausel is excited to continue his lifelong journey of learning and is passionate about the opportunity to treat patients at the highest level possible by performing procedures that are only offered here at the Centeno-Schultz clinic.

Outside of clinic, Dr. Fausel spends most of his time with his two young children and wife. His wife has a paleo food blog of her own, so they enjoy making delicious paleo meals for their family and friends. He and his family also enjoy being as active as possible by finding new hikes, biking, swimming, going to the park and working out at the gym. Dr. Fausel and his family are also looking forward to their first ski season out here in Colorado.

Dr. Jerome is a physiatrist and current fellow in Interventional Orthopedics at the Centeno-Schultz clinic. Originally from New York City, she received her undergraduate degree in studio art from Brown University with a thematic focus on spinal anatomy, microscopic tissue, and the human experience of trauma. After college, she joined Teach for America and taught elementary school in New Mexico for two years. She received her medical degree at the University of Vermont College of Medicine, where she completed an additional year-long student fellowship in anatomic pathology and researched the effects of stretching on connective tissue cellular morphology.

Given her interest in quality of life, function, musculoskeletal anatomy, nutrition, procedural skill, and developing a strong relationship with patients, the field of physical medicine and rehabilitation (PM&R/physiatry) was an obvious choice for Dr. Jerome. She completed her residency in PM&R at Emory University in Atlanta, where she trained at the Shepherd Center, the Emory Spine Center, and the Emory Sports Medicine Center, gaining extensive experience in both general physiatry and image-guided procedural interventions. During residency, she engaged in research regarding vitamin D deficiency, blood clots in hospitalized patients, and the use of regenerative medicine for the treatment of osteoarthritis. She also co-authored a book chapter on the history of regenerative medicine with Dr. Christopher Centeno and Dr. Christopher Williams. In addition to winning an award for her research, Dr. Jerome was the recipient of the Dr. Peszczynski award for outstanding Emory resident in Physical Medicine & Rehabilitation three years in a row and served as chief resident in her final year.

Dr. Jerome is thrilled to be part of the team at the Centeno-Schultz clinic. She believes the thorough patient evaluations and understanding of functional anatomy, combined with the innovative treatments being performed at the clinic, truly offer the best in spine and musculoskeletal care currently available. Outside of work, Dr. Jerome loves to be active in the outdoors and especially enjoys skiing, hiking, and exploring remote places. She loves dogs, enjoys cooking, seeing art, and is a student of yoga.


Centeno-Schultz Fellowship in Interventional Orthopedics – current fellow
2016-2019, Emory University School of Medicine, Atlanta, GA, Residency, Physical Medicine & Rehabilitation
2015-2016, Kaweah Delta Health Care District, Visalia, CA, Internship, Transitional Year
Medical School:
2015 – MD, University of Vermont (UVM) College of Medicine, Burlington, VT
2013-2014, UVM Medical Center, Department of Pathology, Student Fellowship, Burlington, VT
2009- Post-baccalaureate pre-medical certificate, Washington University, St. Louis, MO
2005 – B.A. with honors in visual arts, May 2005, Brown University, Providence, RI


Colorado State medical license


Advanced Cardiac Life Support (ACLS)
Myofascial Release Level I


  • Abramoff B, Krull C, Jerome M, Principe J, Cai Q, Tailor Y. Intervention for Increasing Vitamin D Supplementation in a Deficient Rehabilitation Population: Outcomes of a Quality Improvement Initiative.  PM R. 2019 Jan 27. doi: 10.1002/pmrj.12092. [Epub ahead of print]
  • Jerome MA, Gillenwater J, Laub DR, Osler T, Allan AY, Restrepo C, Campbell A. Primary Cleft Lip and Palate Repair in Assam, India: Does pre-operative anthropometric analysis help identify patients with increased surgical risk? Cleft Palate Craniofac J. 2017 Nov;54(6): 720-25.
  • Persing S, Jerome MA, James T, Weaver D, et al. Surgical Margin Reporting in Breast Conserving Surgery: Does compliance with guidelines change outcomes for patients? The Breast. 2015 Oct;24(5):618-22.
  • Jerome MA, Laub D. Dissecting Cellulitis of the Scalp: case discussion, unique considerations, and treatment options. EPlasty. 2014; June 6;14:ic17.


  • Burke DT, Porter J, Ettefagh L, Jerome MA, Dennison AC. Prevalence of occult lower extremity deep vein thrombosis and identification of clinically relevant factors in patents admitted to an inpatient acquired brain injury rehabilitation program. 13th International Society of Physical + Rehabilitation Medicine World Congress, June 9-13, Kobe, Japan. (poster presenter).
  • Jerome MA, Sussman W, Foster L. Platelet Rich Plasma for the Treatment of Coccydynia: A Case Report. TOBI 10th Annual Symposium, June 6-8, 2019, Chicago, IL. (poster presenter)
  • Jerome MA, Mogbo C, Kneer L. Transient Osteoporosis of Pregnancy: A Case Report of an Unusual but Serious Etiology of Severe Hip Pain. AAP Annual Meeting, February 19-23, 2019, San Jose, PR. (poster presenter)
  • Bradberry D, Jerome MA, Cui D. Identification of Life-Altering Adverse Events in Publication Related to Fluoroscopically-Guided Lumbar Epidural Steroid Injections from 2002 to Current: A Literature Review. 12th International Society of Physical + Rehabilitation Medicine World Congress, July 8-12, Paris, France.(poster presenter).
  • Jerome MA, Ettefagh L, Porter J, Monfared H. Is screening for occult lower extremity deep vein thrombosis (DVT) upon admission to acute inpatient rehabilitation hospitals clinically warranted? 12th International Society of Physical and Rehabilitation Medicine World Congress, July 8-12, Paris, France. (poster presenter)
  • Burke D, Ibekwe E, Jerome MA, Tran M. Using Twitter to Identify Healthcare Consumer Sentiment. 12th International Society of Physical and Rehabilitation Medicine World Congress, July 8-12, Paris, France. (poster presenter)
  • Jerome MA, Bouffard N, Maple R, Badger G, Langevin H. Stretching of connective tissue: Do porcine fibroblasts increase in cross sectional area in response to shear stretch? Association of Academic Physiatrists 2018 Annual Meeting, July 16-20, 2016, Sacramento, CA. (poster presenter)
  • Persing S, Sprague B, James TA, Callas P, Mace J, Jerome MA, Sowden M, Goodwin A, Weaver DL. Surgical Margin Reporting in Breast Conserving Surgery: Does Compliance with Guidelines Affect Re-excision and Mastectomy Rates? American Society of Breast Surgeons, 15th Annual Meeting, April 30-May 4, 2014, Las Vegas, NV. (poster presenter)
  • Campbell A, Restrepo C, Gillenwater J, Jerome MA, Laub DR, Allan A. Primary Cleft Lip Repair: Nutritional Assessment and Surgical Risk in Assam, India. Poster presentation at the 12th International Congress on Cleft Lip/Palate and Related Craniofacial Abnormalities, Orlando, FL, May 6-10, 2013. (poster presenter)
  • Atiyeh A, Blasberg E, Cushanick K, Edberg D, Jerome MA, Ng P, Meehan R, Delaney T, Carney J. “3 Squares Vermont” Food Assistance Usage by Patrons at the Chittenden Emergency Food Shelf. American Public Health Association Annual 140th Annual Meeting, San Francisco, CA, 2012.
  • Colt E, Akram M, Thornton J, Beiling D, Jerome MA, Kausel A, Paladugu S, Tajrishi R, Servetnyk Z, Pi-Sunyer X. Comparison of High Resolution Peripheral Quantitative Computerized Tomography (HR-pQCT) with Dual Energy Photon Absorptiometry (DXA) for Measuring Bone Mineral Density (BMD) in Subjects of Differing Fatness. 93rd Annual Meeting of the Endocrine Society, Boston, MA, June 4-7, 2011.

Google scholar link:

Dr. Pastoriza is a physiatrist with specialty training in interventional pain management and new to Interventional Orthopedics at the Centeno- Schultz clinic. Her interests are primarily in the biomechanics of the human body and in the applications of regenerative medicine for a multitude of injuries in an effort to help patients avoid a more invasive operative intervention. She is from Miami, FL and fluent in both English and Spanish.  She received her undergraduate degree from the University of Florida in Biological Engineering and a minor in Biomechanics.  She competed for the University of Florida Track and Field team as a Javelin thrower and suffered a career ending shoulder injury prompting a more personal interest in biomechanics. Her personal experiences led to an interest in research at the Motion Analysis Laboratory in Gainesville, FL wherein analyzing the throwing mechanics of the baseball and football players helped them to perfect their mechanics. Prior to entering medical school, she worked as a computer programmer at the VA hospital in Gainesville, performing gait analysis kinematics at the Neurorehabilitation Research Center which led to expanding the knowledge of the neuroplasticity that occurs after a stroke.

She attended Lake Erie College of Osteopathic Medicine in Bradenton, FL where she received her medical degree and became an expert in osteopathic manipulations as an adjunct to medical therapies truly taking into consideration all aspects of a patient’s life to help them heal. During this time she was exposed to the healing properties of regenerative medicine after suffering an ankle injury and undergoing a Regenexx procedure to help with instability which helped her avoid a major surgery.  Physical Medicine and Rehabilitation intertwines all aspects of osteopathy along with focusing on improving function and maintaining the highest quality of life given any diagnosis.  She completed her residency in Physical Medicine and Rehabilitation at MetroHealth Medical Center in Cleveland, OH.  Her interest in image-guided procedural interventions led her to complete an Anesthesiology Pain Medicine Fellowship at the University of Alabama in Birmingham. There she became proficient in chronic pain management.

Dr. Pastoriza is excited to embark on this next journey as part of the team at Centeno-Schultz Clinic learning from the regenerative medicine experts. She would like to treat patients with the highest quality of care combining a thorough physical examination and diagnostics to deliver precise image-guided procedures for all musculoskeletal areas of the body.

Outside of the clinic, Dr. Pastoriza spends most of her time with her young son and husband. She and her family enjoy going on bike rides together, along with going to parks and swimming. Dr. Pastoriza’s other hobbies include swimming, cycling, triathlons and crocheting.

Interventional Orthopedics at Centeno-Schultz Clinic – 2019-2020
Anesthesiology Pain Medicine, University of Alabama-Birmingham – 2018-2019

MetroHealth Medical Center, Cleveland, OH – 2015-2018, Physical Medicine and Rehabilitation

Kendall Regional Medical Center, Miami, FL – 2014-2015 – Preliminary General Surgery

Alabama, Colorado, and Ohio

Board Certified by the American Board of Physical Medicine and Rehabilitation
Board Eligible in Sub-specialty of Pain Medicine – pending certification September 2019

English and Spanish (Fluent)

Consider Regenerative Treatment at Centeno-Schultz Clinic and Avoid the Painful Recovery and Downtime Following Surgery

Regenexx® regenerative orthopedic treatments are helping individuals avoid surgery and get back to their daily active lifestyles. These non-surgical treatments are designed to assist the body's natural healing mechanisms by activating and increasing the local cells that are responsible for repairing damaged tissue.

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Westminster, CO 80021


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