More NSAID Problems Reported

motrin heart risk I’ve blogged in the past concerning Motrin heart risks and the surprising cardiac risks of the other common NSAID’s such as Aleve, Naprosyn, and Celebrex. On the heels of those studies comes another one this morning out of the journal Circulation. In this study, researchers looked at patients with a prior heart attack and whether NSAID drug use had an impact on the rate of future heart attacks. This study included more than 83,000 Danish heart attack survivors, some 42.3% of which took NSAID’s. Among the widely used pain relievers, the researchers found that the risk of a repeat heart attack increased 3-4 fold with Voltaren and that the increased risk happened immediately and continued to rise through 14 weeks of use. Celebrex was even riskier for these patients. Motrin appeared to be the safest, but still elevated heart attack risk through week 6, while Naprosyn increased the risk of a repeat heart attack only through the first week of use. The authors concluded that if you’ve had a heart attack, there really isn’t a safe NASID drug. What are the other options? Joe Maroon, who is a neurosurgeon at the University of Pittsburgh, published a nice study showing that he was able to get 60% of his low back pain patients off of an NSAID by prescribing high quality fish oils. As a result, my personal opinion would be to go buy some good fish oil and lay off the Motrin, Aleve, and Celebrex!

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Chris Centeno, MD is a specialist in regenerative medicine and the new field of Interventional Orthopedics. Centeno pioneered orthopedic stem cell procedures in 2005 and is responsible for a large amount of the published research on stem cell use for orthopedic applications. View Profile

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