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More Fake PRP Studies

I’ve covered a few different “PRP” studies that didn’t actually use real PRP. However, none were as ridiculous as a study that was recently published in JAMA on knee arthritis. Let’s dig in. When is PRP not PRP? PRP stands for platelet-rich plasma. The idea is supposed to be that PRP concentrates platelets many times…
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Happy Thanksgiving!

It’s our day to give thanks. So let’s review the history of our modern Thanksgiving and then I’ll discuss what I’m thankful for. Let’s dig in. The History of Our Modern Thanksgiving To read about the actual history of the pilgrims, read this post. In 1777 the Continental Congress declared the first American Thanksgiving holiday…
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Being Thankful For Your Shoes

This is the week to give thanks for all that we have. Today we’ll look at an Olympian who was thankful for two mismatched shoes. Let’s dig in. It’s Almost Hard to Conceptualize the Past in Terms of Today Just a century ago, Americans had far less. Most were thankful for a good pair of…
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The First Thanksgiving

I’m headed out today for a much-needed vacation, so I’ll be blogging quite a bit less this week. However, this morning I thought I would take a break from all of the medical and science stuff and dive into the first Thanksgiving. Let’s dig in. What Is Thanksgiving? You know me, I’m that 12-year-old kid…
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How Another Bad Surgical Orthobiologics Paper Can Teach Us About QC

If there’s one journal that keeps regularly getting it wrong on orthobiologics, it’s the journal Arthroscopy. So let’s dig into a recent paper published in that journal. By understanding why it can’t support its conclusions we’ll learn quite a bit about the quality control of a bone marrow aspiration. Why? Because if you’re a doctor…
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What Is Procenta? What Is Human Tissue Therapy (HTT)? Why Is a Former Employee Mixed Up in This?

This week, I had a colleague send me information about yet another birth tissue company selling a product for use in treating orthopedic injuries. The sales rep claimed to my colleague that this product, called Procenta, was “FDA Approved” for that purpose. Let’s dig in. What Is Procenta? Procenta is a placental tissue sold by…
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Welcome to the Hip Osteonecrosis BMC Club Yale!

One of the trends of the last 5 years is seeing more and more universities add the use of PRP and Bone Marrow Concentrate to their day-to-day patient offerings. One of those treatments that we’ve been using for more than a decade is a Bone Marrow Concentrate injection to treat Osteonecrosis of the hip. Now…
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When Lab Research Scientists Play Doctors -The Knoepfler Files

Do you remember that famous 1970s TV quote, “I’m not a doctor, but I play one on TV”? Well, that’s what some research scientists are doing. Let’s dig into that today. Ph.D. vs. M.D. A Ph.D. is someone who begins with a Bachelors in Science degree and then takes additional graduate-level course work in their…
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