Interventional Orthobiologics Articles

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Can Young Blood Transfusions Make You Younger?

There’s been an experimental result that medical science has known about for a long time that has shaken up our basic understanding of biology. It’s called Heterochronic Parabiosis and it’s basically hooking an old animal up to a younger one. Several existing experiments suggested that this made the old animal younger, but new research questions…read more

Rebutting Misinformation in Orthopedic Journals: Ittleman and Shapiro

Orthobiologic treatments represent a disruptive technology that I have blogged on dozens of times. Given that many patients who used to get invasive orthopedic surgery are now skipping those procedures and instead using interventional orthobiologics, orthopedic surgeons have varied reactions to this new playing field. We’ll explore those issues today in the context of an…read more

VittiLabs, the Sopranos, and an FDA Warning Letter

I’ve blogged quite a bit on the crumbling amniotic and umbilical cord fake stem cell market. Despite peer-reviewed research demonstrating that these products clearly have no stem cells, throughout social media, we still see patients who are getting bombarded by influencers who claim they are loaded with young and vital stem cells. One of the…read more

Bone Marrow Stem Cell Dose Matters in Knee Osteoarthritis

If there’s one overarching theme in orthobiologics that I have been discussing for almost two decades, it’s that measuring and delivering higher doses are critical for success. Despite this, 99% of physicians who offer these procedures don’t know what dose they’re delivering and use bedside kits that can only achieve low doses. Today we’ll go…read more

PRP Injections for Knee ACL Tears: A Few Sandwiches Short of a Picnic

When I was in medical school I had a British girlfriend who used to use the very English expression, “A few sandwiches short of a picnic”. That saying immediately came to mind as I reviewed a new study published by orthopedic surgeons in the middle east as they compared ACL surgery to PRP injection. It…read more

The Low Back Pain Circulus in Probando Experiment

What if you lied to your patients about what was wrong with them? Meaning, what if you told them there was nothing wrong when you as the doctor had no idea if that was accurate? What impact would that have on them? That was recently studied in an RCT on the biopsychosocial model of pain…read more

Does Testosterone Help Orthobiologic Procedures?

The same patient who asked the question about PRP vs BMC and ligament healing yesterday also asked about whether taking testosterone could help with healing after an orthobiologic procedure. That same prolotherapy physician who launched the last blog had also claimed that there was no doubt that the science showed that testosterone supplementation helped his…read more

PRP vs BMC for Ligament Healing

I love writing about what I experience on a day-to-day basis. A patient recently wrote to me claiming that a prolotherapy physician had told him that PRP injections were clearly superior to Bone Marrow Concentrate for helping ligaments heal. Hence, I figured it was time for a formal deep dive to help patients understand the…read more
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