The Centeno-Schultz Interventional Orthopedic Fellowships

The Centeno-Schultz Clinic was the first practice in the U.S. to use stem cells for orthopedic injuries by treating joints and low back disc problems back in 2005.

Since then, we’ve continued to advance the science of regenerative medicine. We’ve made many technological innovations and advances in how cells are harvested, processed, and re-implanted. We’ve developed and patented new procedural techniques and devices. We run a state of the art stem cell biology facility that includes a large clean room processing space and a separate privately funded university-style research lab as well as a dedicated research team. This research division gives us the knowledge needed to custom-fit cell-based therapies to our patients rather than trying to fit our patients into to what a simple, automated machine can produce.

Rather than blindly injecting stem cells into joints and hoping that they end up in the right place, we’ve developed new interventional techniques to precisely place cells in various areas of the MSK system using ultrasound and fluoroscopy. We pioneered the percuteneous placement of stem cells into the ACL ligament. This technique simply didn’t exist before we realized that many of these patients could avoid surgery by accurately placing stem cells into the ligament to heal partial and full thickness tears. Another example of our innovation is in-house research that lead to a process to dramatically increase the number of stem cells that could be isolated from bone marrow in a same day procedure. Regenexx is dedicated to innovation and is constantly improving our ability to heal orthopedic injuries without invasive and often ineffective surgeries.

What is Interventional Orthopedics?

We believe that due to advances in regenerative medicine, the rapid evolution in interventional cardiology that happened in the 1980-90s to today will happen in orthopedic care. In the 1980s, most major heart problems were treated with CABG. However, a quiet revolution took place that changed the status quo. Cardiologists began experimenting with percutaneous angioplasty. With every passing year from the 1980s through the 1990s, fewer and fewer patients needed open heart surgery and a new medical specialty was born–interventional cardiology. As time went by, more and more surgical procedures were performed percutaneously. We believe the same thing is happening in orthopedic care with Interventional Orthopedics replacing more and more surgical procedures through the use of various platelet, cytokine, and growth factor treatments as well as stem cells. We also believe that an Interventional Orthopedics expert needs to be able to place a needle and regenerative therapeutics everywhere from the C0-C1 facet joint to the ankle TT joint or in any accessible tendon or ligament under fluroroscopic or ultrasound guidance. In summary, our fellowships are the best of an interventional spine fellowship combined with the best of a sports fellowship but focused on the future by providing extensive experience in PRP and stem cell treatment using image guidance.

Interventional Orthopedics Traditional Fellowship

The fellowship being offered by the Centeno-Schultz Clinic (CSC) in Interventional Orthopedics and Regenerative Medicine is 12 months long, interviews typically occur in the first part of the year with the final selections made by early fall.  The fellowship year will be broken up as follows:

60% clinical care with a focus on the use of various percutaneous stem cell and platelet technologies in regenerative medicine.

40% research in which the fellow must complete a research project under CSC supervision and submit same for publication by June 2019. This portion includes interaction with the on-site stem-cell-research lab.

Qualifications: Board certified in Physical Medicine and Rehabilitation, Anesthesiology Pain Medicine, or Family Practice, Sports Medicine. The applicant must have basic spine, fluoroscopy, and MSK ultrasound skills mastered. Prior regenerative medicine experience (simple regenerative techniques such as PRP or prolotherapy) is helpful. At least 100 proctored interventional spine cases under fluoroscopic guidance would be helpful.

Salary: 75K

Job Prospect: The applicant may or may not be offered a position as a staff physician at CSC after completion of the fellowship depending on performance in the fellowship and the needs of the clinic. Other job opportunities in other parts of the country within the Regenexx network are also available.

Benefits: 401K, medical, dental, vision and an annual luxury health club membership included

Location: Denver/Boulder, Colorado

Applicants should have basic training in needle guidance via ultrasound and fluoroscopy and have successfully completed a PMR residency program or similar.

To apply or for further information, please contact Micah Zackroff at

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