Stem Cell Therapy
Bone marrow concentrate containing mesenchymal stem cells promotes tissue repair and regeneration by harnessing the body’s natural healing mechanisms. At Regenexx, concentrated orthobiologics—substances derived from a patient's bone marrow or blood—are used to address injuries, degenerative diseases, and other health issues. These treatments, delivered through image-guided injections, offer a non-surgical option for various conditions.
Subscribe to the BlogBlogging from the Caymans Again
Twice a year now, I head down to Grand Cayman to treat patients with culture-expanded stem cells. Why make this trip? What’s different? Let’s dig in. What are Culture Expanded Stem Cells? There are stem cells in bone marrow concentrate which we use widely in the United States to help patients heal from a variety…read more
Is Bone Marrow Concentrate a Stem Cell Therapy?
This has been an interesting few years with regard to the regulations behind using the term “stem cell therapy”. It’s also been an interesting scientific ride as well. Today I’ll review the pure science of whether bone marrow concentrate is a stem cell therapy. I’ll cover the concept that bone marrow concentrate contains stem cells…read more
The Alien Abduction Model of DDD: Why Cellular Drug Trial Results Have Been Underwhelming
Let’s say that you’re sleeping one night and get awoken by an alien in your bedroom who takes you back to the mothership for experiments on your low back. That’s pretty much what we’ve been doing with animal degenerative disc disease research for decades. It’s this artificial DDD model that has caused many cell therapy…read more
Can Young Blood Transfusions Make You Younger?
There’s been an experimental result that medical science has known about for a long time that has shaken up our basic understanding of biology. It’s called Heterochronic Parabiosis and it’s basically hooking an old animal up to a younger one. Several existing experiments suggested that this made the old animal younger, but new research questions…read more
Seamonkeys and Oral Stem Cell Pills from New Zealand
I used to love Sea-monkeys as a kid. They would come to life out of a little packet of dehydrated eggs when placed in seawater. An ad this week on Facebook selling oral “live” stem cell pills is claiming that a pill can repair your body using placental stem cells from deer. So is it…read more
CFU-f 101: To Be an Orthobiologics Expert You MUST Learn This
The blind leading the blind is one of my favorite expressions. As one of the founders of this field of interventional orthobiologics, the fact that this statement applies to much of our existing orthobiologics education is concerning to me. Nowhere is this more true than the concept of stem cell dose and CFU-f assays. Hence,…read more
Can You Easily Determine MSC Content of BMC at the Bedside?
Dose is a key metric in medicine. However, dosing cells isn’t used in most of orthobiologics. However, is that about to change? Will it be possible to get a dose of stem cells at the bedside when using BMC or Mfat? Let’s dig in. Dose Matters Determining the stem cell content of Bone Marrow Concentrate…read more
Umbilical Cord MSCs Sales 2.0: Using the Expanded Access Program?
You have read here many times about the fraudulent claims of umbilical cord tissue vendors that they are selling products with millions of young and vital mesenchymal stem cells. That was followed by the FDA crackdown last year and all seemed quiet for a while. However, now we’re seeing a new business plan emerge that…read more
