COVID-19 UPDATE: Regenexx is committed to the health and safety of our patients. You may now be seen in clinic or via telemedicine for virtual/online or phone visits.
LEARN MORE
Our physicians are available via telemedicine to continue to give you the care you need during this difficult time. Learn more.

Periodic Knee Injections of Stem Cells Delay Cartilage Degeneration

By /

stem cells delay cartilage degeneration

Japanese researchers presented a research study this week at the Orthopedic Research Society that showed periodic injections of stem cells delay cartilage degeneration in knee osteoarthritis. While this was an animal model, it fits with our 8 year experience of using stem cells in knee arthritis. We have always thought, especially in patients with more severe knee arthritis, that replacing the “stem cell reserve” in the knee was critical. In this theory of knee degenerative disease, the knee is no longer able to maintain itself due in part to fewer functional stem cells, thus the knee sprials out of control, creating a toxic stew of catabolic breakdown chemicals.

There were some other very good research studies at ORS this year. In another, researchers at Stanford found that “adipokines” (cell signaling chemicals that are more commonly found in obese patients) breakdown the meniscus more than knee cartilage. What’s interesting here is that in heavier patients, we often do see the meniscus fail first. This theory would argue that arthritis in heavier patients is not only mechanical (more weight equals more wear and tear on joints), but also chemical.

In yet another ORS paper, researchers found that short bursts of high intensity activity wear down joint replacement prostheses faster than sustained activity. The concerning part of this study was that fast walking predicted more device breakdown (as measured by a sensor on the patient). What’s the hallmark of the younger and more active patients now being targeted by joint replacement manufacturers? They frequently exercise in more intense bursts, walk faster, run, etc… So these findings are a bit concerning for younger patients with knee or hip replacements who want to remain active.

Get health and wellness information from a trusted source.

By submitting the form, you are agreeing that you read and consent to our Privacy Policy. We may also contact you via email, phone, and other electronic means to communicate information about our products and services. We do not sell, or share your information to third party vendors.

Is Regenexx Right For You?

Request a free Regenexx Info Packet

REGENEXX WEBINARS

Learn about the #1 Stem Cell & Platelet Procedures for treating arthritis, common joint injuries & spine pain.

Join a Webinar

RECEIVE BLOG ARTICLES BY EMAIL

Get fresh updates and insights from Regenexx delivered straight to your inbox.

Subscribe to the Blog

CONTACT US

9035 Wadsworth Pkwy #1000
Westminster, CO 80021
888-525-3005

FOLLOW US

Copyright © Regenexx 2020. All rights reserved. | Privacy Policy

*DISCLAIMER: Like all medical procedures, Regenexx® Procedures have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.

Providers listed on the Regenexx website are for informational purposes only and are not a recommendation from Regenexx for a specific provider or a guarantee of the outcome of any treatment you receive.

LinkedIn
Email