Orthobiologics

Your body is built to repair damage to itself. In some cases, however, due to the site or severity of your injury or a reduction in these abilities with age, your body can’t keep up with the damage that is done.

Regenexx treatments use your body’s natural healing agents to repair or mitigate damage by concentrating and focusing them at the exact site of your injury. This approach allows for natural, efficacious healing without the need for surgery.

Bone-marrow Stem Cells

Stem cells are cells that can turn into other types of cells and can also orchestrate a repair response. As such, they work as your body’s primary means of repairing damage. There are different types of stem cells, but for treating orthopedic injuries, the only one with demonstrated efficacy is mesenchymal stem cells (MSC).

Based on our extensive experience, the most effective MSCs are derived from bone marrow. These cells can turn into bone, cartilage, muscle, tendons, or ligaments. Regenexx draws bone marrow from your hip bones, processes it in our lab to derive 5-20 times more stem cells per unit volume injected than can be achieved by a bedside centrifuge machine most physicians use. These stem cells are then injected using precise image guidance into the precise area of your injury to rebuild, repair, or mitigate the effects of damaged tissue. Our extensive research using MSCs derived from bone marrow has shown excellent outcomes in treating all but the most severe orthopedic injuries.

Culture Expanded Stem Cells

Regenexx offers a licensed site in Grand Cayman that can grow stem cells to bigger numbers (called culture expansion) and where those same cells can be safely stored. This technology is used in select patients, including 1.) patients with more severe orthopedic conditions, 2.) patients who want to treat multiple joints, 3.) patients who want to store and save cells for future treatments. This procedure is not US FDA approved (but is the subject of an FDA approved phase 1-2 clinical trial) and is permitted in Grand Cayman as the practice of medicine. Additionally, their U.S. board certified Regenexx physicians are licensed to practice in the Cayman Islands and perform this advanced treatment.

Adipose-Derived Stem Cells

While adipose- or fat-derived stem cells have been shown to be much less effective than bone-marrow-derived stem cells at turning into bone, cartilage, muscle, tendon, or ligament as a means of repairing orthopedic injuries, in some cases, these cells can also be used effectively as a part of a larger treatment plan for orthopedic injuries to create a fat graft that supports and holds in place other structures and allows them to heal appropriately. Regenexx’s expert physicians are well versed in the best ways to use these cells to support your recovery.

Platelet-Rich Plasma

Regenexx PRP

Platelet-rich plasma (PRP) is created by concentrating the platelets in your blood to enhance healing. These platelets have growth factors that can kick-start your normal healing process to encourage your body to heal itself. Regenexx’s proprietary lab processing allows us to remove nearly all of your white and red blood cells so that what is being injected contains only what your body needs to help repair damage. This difference between Regenexx’s super-concentrated PRP and most other PRP is visible. The usual standard fare PRP is reddish in color because it still contains a significant number of red blood cells while Regenexx’s PRP is amber in color. In addition, Regenexx PRP is more concentrated by a factor of 3X – 5X above what a basic bedside centrifuge machine can produce for physicians. Our in-vitro experiments demonstrate that this produces better tissue healing in tendon injuries and better stimulation of the local stem cells.

Platelet Lysate

Platelet lysate is a highly specialized derivative of platelet-rich plasma (PRP). Normal PRP isolates platelets from the blood which slowly release growth factors into the site of the injury over the course of roughly one week. In some cases, however, our research shows that a faster, more intense release of healing factors creates a better healing response. Platelet lysate accomplishes this by stripping all of the growth factors out of platelets and making these available for immediate use. Regenexx’s proprietary platelet-lysate processing technology is now on its third and fourth generation as we’ve learned better ways to encourage fast release of growth factors.

Extra-cellular Matrix (ECM)

An ECM is a scaffold on which cells can grow. We use a few different ECM products. One is derived from amniotic membrane. While this doesn’t contain stem cells, it does contain proteins and growth factors that we believe can help platelets or stem cells in certain clinical scenarios like tendon repair.

Read More About this Topic

Regenerative procedures are commonly used to treat musculoskelatal trauma, overuse injuries, and degenerative issues, including failed surgeries.
Select Your Problem Area
Shoulder

Shoulder

Many Shoulder and Rotator Cuff injuries are good candidates for regenerative treatments. Before considering shoulder arthroscopy or shoulder replacement, consider an evaluation of your condition with a regenerative treatment specialist.

  • Rotator Cuff Tears and Tendinitis
  • Shoulder Instability
  • SLAP Tear / Labral Tears
  • Shoulder Arthritis
  • Other Degenerative Conditions & Overuse Injuries
Learn More
Cervical Spine

Spine

Many spine injuries and degenerative conditions are good candidates for regenerative treatments and there are a number of studies showing promising results in treating a wide range of spine problems. Spine surgery should be a last resort for anyone, due to the cascade of negative effects it can have on the areas surrounding the surgery. And epidural steroid injections are problematic due to their long-term negative impact on bone density.

  • Herniated, Bulging, Protruding Discs
  • Degenerative Disc Disease
  • SI Joint Syndrome
  • Sciatica
  • Pinched Nerves and General Back Pain
  • And more
Learn More
Knee

Knees

Knees are the target of many common sports injuries. Sadly, they are also the target of a number of surgeries that research has frequently shown to be ineffective or minimally effective. Knee arthritis can also be a common cause for aging athletes to abandon the sports and activities they love. Regenerative procedures can be used to treat a wide range of knee injuries and conditions. They can even be used to reduce pain and delay knee replacement for more severe arthritis.

  • Knee Meniscus Tears
  • Knee ACL Tears
  • Knee Instability
  • Knee Osteoarthritis
  • Other Knee Ligaments / Tendons & Overuse Injuries
  • And more
Learn More
Lower Spine

Spine

Many spine injuries and degenerative conditions are good candidates for regenerative treatments and there are a number of studies showing promising results in treating a wide range of spine problems. Spine surgery should be a last resort for anyone, due to the cascade of negative effects it can have on the areas surrounding the surgery. And epidural steroid injections are problematic due to their long-term negative impact on bone density.

  • Herniated, Bulging, Protruding Discs
  • Degenerative Disc Disease
  • SI Joint Syndrome
  • Sciatica
  • Pinched Nerves and General Back Pain
  • And more
Learn More
Hand & Wrist

Hand & Wrist

Hand and wrist injuries and arthritis, carpal tunnel syndrome, and conditions relating to overuse of the thumb, are good candidates for regenerative treatments. Before considering surgery, consider an evaluation of your condition with a regenerative treatment specialist.
  • Hand and Wrist Arthritis
  • Carpal Tunnel Syndrome
  • Trigger Finger
  • Thumb Arthritis (Basal Joint, CMC, Gamer’s Thumb, Texting Thumb)
  • Other conditions that cause pain
Learn More
Elbow

Elbow

Most injuries of the elbow’s tendons and ligaments, as well as arthritis, can be treated non-surgically with regenerative procedures.

  • Golfer’s elbow & Tennis elbow
  • Arthritis
  • Ulnar collateral ligament wear (common in baseball pitchers)
  • And more
Learn More
Hip

Hip

Hip injuries and degenerative conditions become more common with age. Do to the nature of the joint, it’s not quite as easy to injure as a knee, but it can take a beating and pain often develops over time. Whether a hip condition is acute or degenerative, regenerative procedures can help reduce pain and may help heal injured tissue, without the complications of invasive surgical hip procedures.

  • Labral Tear
  • Hip Arthritis
  • Hip Bursitis
  • Hip Sprain, Tendonitis or Inflammation
  • Hip Instability
Learn More
Foot & Ankle

Foot & Ankle

Foot and ankle injuries are common in athletes. These injuries can often benefit from non-surgical regenerative treatments. Before considering surgery, consider an evaluation of your condition with a regenerative treatment specialist.
  • Ankle Arthritis
  • Plantar fasciitis
  • Ligament sprains or tears
  • Other conditions that cause pain
Learn More

Is Regenexx Right For You?

Request a free Regenexx Info Packet

REGENEXX WEBINARS

Learn about the #1 Stem Cell & Platelet Procedures for treating arthritis, common joint injuries & spine pain.

Join a Webinar

RECEIVE BLOG ARTICLES BY EMAIL

Get fresh updates and insights from Regenexx delivered straight to your inbox.

Subscribe to the Blog

FOLLOW US

Copyright © Regenexx 2019. All rights reserved. | Privacy Policy

*DISCLAIMER: Like all medical procedures, Regenexx® Procedures have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.

Providers listed on the Regenexx website are for informational purposes only and are not a recommendation from Regenexx for a specific provider or a guarantee of the outcome of any treatment you receive.