Fat Stem Cell Injections: Are Aged Adipose Stem Cells as Good as Young Ones?

By /

fat stem cell injections

Fat stem cell injections have been all the rage lately for everything from cosmetics to multiple sclerosis to arthritis. Many of the patients who want to have their fat stem cells injected to treat something are older. Does this make a difference or are older fat stem cells as good as younger cells?

The issue of age and stem cell function is all over the map. You can find studies that purport to show that age makes a huge difference and other studies that seem to show it makes no or little difference in stem cell function or potency. Our own clinical data from our advanced treatment registry shows that it depends on what you’re treating. For example, age doesn’t seem to have an effect when using stem cells to treat knee arthritis, but older age does have an effect when the target problem is hip arthritis. 

A new study sought to the answer this question for patients who might get adipose stem cells for heart disease. The authors isolated fat stem cells from 31 patients aged 2-81 years old. They then looked at the ability of the cells to differentiate into fat cells and bone, which all patient samples could accomplish. They noted that the fat stem cells from older patients had shorter telomeres (the “clock” at the end of the DNA strand that only allows only so many copies to be made). This meant that these cells were biologically older and closer to a state where they could no longer keep dividing. The ability of the growth factors capable of telling the body to produce new blood vessels (an important thing for a heart disease patient) was less in the older fat stem cells. This didn’t seem to be because older fat stem cells produced less growth factors, but because they produced more chemicals that deactivated these same growth factors.

The upshot? For the lab metrics that would define the ability of fat stem cells to help someone grow new blood vessels, age did seem to make a difference. Whether this translates into a less clinical efficacy is unknown.

This blog post provides general information to help the reader better understand regenerative medicine, musculoskeletal health, and related subjects. All content provided in this blog, website, or any linked materials, including text, graphics, images, patient profiles, outcomes, and information, are not intended and should not be considered or used as a substitute for medical advice, diagnosis, or treatment. Please always consult with a professional and certified healthcare provider to discuss if a treatment is right for you.

Get health and wellness information from a trusted source.

By submitting the form, you are agreeing that you read and consent to our Privacy Policy. We may also contact you via email, phone, and other electronic means to communicate information about our products and services. We do not sell, or share your information to third party vendors.

Category: Hip, Knee, Latest News

Is Regenexx Right For You?

Request a free Regenexx Info Packet

REGENEXX WEBINARS

Learn about the #1 Stem Cell & Platelet Procedures for treating arthritis, common joint injuries & spine pain.

Join a Webinar

RECEIVE BLOG ARTICLES BY EMAIL

Get fresh updates and insights from Regenexx delivered straight to your inbox.

Subscribe to the Blog

CONTACT US

9035 Wadsworth Pkwy #1000
Westminster, CO 80021
888-525-3005

FOLLOW US

Copyright © Regenexx 2020. All rights reserved. | Privacy Policy

*DISCLAIMER: Like all medical procedures, Regenexx® Procedures have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.

Providers listed on the Regenexx website are for informational purposes only and are not a recommendation from Regenexx for a specific provider or a guarantee of the outcome of any treatment you receive.

LinkedIn
Email
TO TOP