What happens to the Stem Cells when you Get Someone Else’s Cells?

By /

mass manufactured stem cells

I’ve blogged before on the problems with allogeneic stem cells. While this is the preferred Pharma business model for stem cells because it allows cells to be mass manufactured and distributed like drugs, is it a good idea? First, while it’s been hyped that donor stem cells aren’t rejected like someone else’s heart or kidney, this is only partially true. For example, a recent research study showed that stem cells from a donor did cause the host to react negatively toward the cells (the host tried to kill them off). We also know that the genes of the donor stem cells stay working in the host. Why is this a concern? You’re buying all of your genetic predispositions plus that of the donor. Did he or she have cells that code for a cancer later in life? Who knows? We certainly don’t know at this early stage of development of routine genetic screens. In addition, for cells that are mass manufactured, there is no requirement for the companies selling these cells to screen for these possible genetic diseases. A recent study further continues this same cause for concern. The researchers looked at two patients who were given someone else’s stem cells to treat transplant rejection who later died of infection. The donor’s cells were still present in many of the patient’s organs a year later. With a traditional small molecule chemical drug this is almost never a concern, meaning you don’t worry about the drug still being in your system months or years after you’ve taken the drug. This is not the case with cell drugs. In addition, unlike getting someone else’s kidney where you know the risks (mainly of getting really sick from rejection), these genetic risks are being largely swept under the rug by the Pharma industry gearing up for mass manufactured stem cells.

The upshot? Allogeneic stem cells remain a concern and it appears that every month or two another study comes out that raises more issues. While this is a convenient way to mass produce and distribute cells like drugs, it’s looking like the mounting science is questioning the wisdom of this decision.

Join us for a free Regenexx webinar.

If you have questions or comments about this blog post, please email us at [email protected]

NOTE: This blog post provides general information to help the reader better understand regenerative medicine, musculoskeletal health, and related subjects. All content provided in this blog, website, or any linked materials, including text, graphics, images, patient profiles, outcomes, and information, are not intended and should not be considered or used as a substitute for medical advice, diagnosis, or treatment. Please always consult with a professional and certified healthcare provider to discuss if a treatment is right for you.

Get Blog Updates by Email

By submitting the form, you are agreeing that you read and consent to our Privacy Policy. We may also contact you via email, phone, and other electronic means to communicate information about our products and services. We do not sell, or share your information to third party vendors.

Category: Latest News
Copyright © Regenexx 2021. All rights reserved.

CONTACT INFORMATION

Address

9035 Wadsworth Pkwy #1000
Westminster, CO 80021

Phone

*DISCLAIMER: Like all medical procedures, Regenexx® Procedures have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.

Providers listed on the Regenexx website are for informational purposes only and are not a recommendation from Regenexx for a specific provider or a guarantee of the outcome of any treatment you receive.

LinkedIn
Email
TO TOP