COVID-19 UPDATE: Regenexx is committed to the health and safety of our patients. You may now be seen in clinic or via telemedicine for virtual/online or phone visits.
Our physicians are available via telemedicine to continue to give you the care you need during this difficult time. Learn more.

More Research that Bone Marrow Beats Fat for Orthopedic Applications

By /

bone marrow beats fat for orthopedic applications

Despite all the hype, Fat stem cells are great for some things, and not for others. The same is true for Bone Marrow stem cells. The trick is using the right type of stem cells, for the right thing. In a new study out of China, there is yet more data showing that bone marrow stem cells outperform adipose stem cells for bone and cartilage repair. Why?

The general Bone Marrow vs Fat Stem Cell debate makes sense in that Mesenchymal (MSC’s) are plentiful in both tissue sources. It’s when that debate narrows to specific applications that it loses steam. Specific types of stem cells simply do different things, and while there are actually more MSC’s in fat than bone marrow as a percentage of nucleated cells, there are many fewer nucleated cells in fat — meaning that both have similar stem cell content.

The new study set up a direct head to head comparison of the biological characteristics of adipose and bone marrow MSC’s to evaluate their potential for regenerative medicine applications. After evaluating many different characteristics for use in cell therapy, their findings demonstrated that the two different types of stem cells had very different differentiation potential. Adipose MSC’s cells grew more easily, and had better immune system potential. Each source contained different but equal growth factors. Bone Marrow MSC’s had a much greater biological advantage in osteogenic (bone making), and chondrogenic (cartilage making) differentiation characteristics.  They concluded that the different characteristics should be considered when selecting the tissue source of MSC’s for different regenerative medical applications.

The upshot?  This was an important study that mirrors the finding of many other studies. We now have 10 studies showing that bone marrow stem cells are better for orthopedic purposes than fat stem cells. We’ve tested both adipose and bone marrow stem cells extensively for orthopedic applications in the lab and have used both in treatment. We found the use of, or addition of, adipose stem cells provided no benefit over bone marrow stem cells. So if you are looking for a face lift, a little filler in your frown lines, or even a stem cell heart procedure, we can’t help you, but regrettably, neither can the docs using fat do much for your knees.

Get health and wellness information from a trusted source.

By submitting the form, you are agreeing that you read and consent to our Privacy Policy. We may also contact you via email, phone, and other electronic means to communicate information about our products and services. We do not sell, or share your information to third party vendors.

Category: Latest News

Leave a Reply

Your email address will not be published. Required fields are marked *

Is Regenexx Right For You?

Request a free Regenexx Info Packet


Learn about the #1 Stem Cell & Platelet Procedures for treating arthritis, common joint injuries & spine pain.

Join a Webinar


Get fresh updates and insights from Regenexx delivered straight to your inbox.

Subscribe to the Blog


9035 Wadsworth Pkwy #1000
Westminster, CO 80021


Copyright © Regenexx 2020. All rights reserved. | Privacy Policy

*DISCLAIMER: Like all medical procedures, Regenexx® Procedures have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.

Providers listed on the Regenexx website are for informational purposes only and are not a recommendation from Regenexx for a specific provider or a guarantee of the outcome of any treatment you receive.