COVID-19 UPDATE: Regenexx is committed to the health and safety of our patients. You may now be seen in clinic or via telemedicine for virtual/online or phone visits.
LEARN MORE
Our physicians are available via telemedicine to continue to give you the care you need during this difficult time. Learn more.

Is using someone else’s Young Stem Cells better than using your own Old Stem Cells?

By /

Receive a Regenexx® Patient Info Packet by email and learn why it's a superior regenerative solution.

By submitting the form, you are agreeing that you read and consent to our Privacy Policy. We may also contact you via email, phone, and other electronic means to communicate information about our products and services. We do not sell, or share your information to third party vendors.

young stem cells better than your own

Are another person’s young stem cells better than your own?  Could you use them to get around the fact that your old stem cells may not be as good? Much of the stem cell pharma industry is focused on using donor stem cells from young patients and growing these to massive numbers in bio reactors. They call this “scalability”, meaning that you can distribute these young cells in vials into existing drug distribution pipelines. From a business standpoint this makes sense, but does it make sense from a scientific standpoint? The concept that young stem cells perform better than old ones has some prima facie evidence. In many papers, older stem cells have less ability to perform certain functions when compared to younger stem cells. However, is it really that simple? Likely not. Stem cells communicate extensively with their local environment. For example, they can detect if the local stuff that cradles them (extra-cellular matrix-ECM) is young or old and respond according. Stem cell research is compelling and this novel observation was made in a landmark paper from last year. The researchers took old stem cells and exposed them to young ECM and the stem cells went from plodding along like grandpa stem cells to regaining the capabilities of younger stem cells! This week another paper in this “young stuff makes old cells young” genre was published. For this paper, the researchers focused on the specific cellular signals that cause the “young/old” switch on the stem cells to be in the “on” or “off” position. The quote by the lead investigator says it all, “The findings suggest, for example, that putting new or young stem cells into an old environment — that of an aged patient — might not lead to the best outcome in tissue regeneration”. Meaning that many of these bio pharma approaches may ultimately fail as putting young stem cells in an old environment may not be any better than putting old stem cells into the same environment. For our part, we have always respected the micro environment in our stem cell treatments. We go through great lengths to test various medications and other adjuvants with stem cells in our advanced lab to determine ways to optimize function. The upshot? You can teach old stem cells new tricks, but young stem cells easily learn bad tricks from old digs.

Category: Latest News

Is Regenexx Right For You?

Request a free Regenexx Info Packet

REGENEXX WEBINARS

Learn about the #1 Stem Cell & Platelet Procedures for treating arthritis, common joint injuries & spine pain.

Join a Webinar

RECEIVE BLOG ARTICLES BY EMAIL

Get fresh updates and insights from Regenexx delivered straight to your inbox.

Subscribe to the Blog

CONTACT US

9035 Wadsworth Pkwy #1000
Westminster, CO 80021
888-525-3005

FOLLOW US

Copyright © Regenexx 2020. All rights reserved. | Privacy Policy

*DISCLAIMER: Like all medical procedures, Regenexx® Procedures have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.

Providers listed on the Regenexx website are for informational purposes only and are not a recommendation from Regenexx for a specific provider or a guarantee of the outcome of any treatment you receive.

LinkedIn
Email