Knee Osteoarthritis

Bone Marrow Stem Cell Dose Matters in Knee Osteoarthritis

If there’s one overarching theme in orthobiologics that I have been discussing for almost two decades, it’s that measuring and delivering higher doses are critical for success. Despite this, 99% of physicians who offer these procedures don’t know what dose they’re delivering and use bedside kits that can only achieve low doses. Today we’ll go…read more

Playing With Knee Steroid Data, Et Tu Harvard?

A few years back a seminal paper was published showing what many physicians knew was an issue, that mega-dose steroids destroy knee cartilage (1). However, this was a HUGE problem for many physicians who have been injecting this stuff with wild abandon for many years. Hence, it was only a matter of time before papers…read more

Analyzing CCI Procedure Failures: The SpaceX Approach

[The above video is a summary of this blog.] In any real medical procedure, there are always analyses of why patients fail to respond. This week I went through that process for a unique procedure I developed to help patients suffering from Craniocervical Instability (CCI). Let’s dig into that analysis and learn what it tells…read more

The Academic Low Dose PRP Knee OA Problem Is Alive and Well-The Lewis Et al JBJS Paper

Academics are hopelessly behind the modern practice of orthobiologics. While there are all sorts of reasons for this, the problem is that it continuously shows up in the literature. This morning we’ll cover a new knee arthritis “PRP” study and review an older one that both made the mistake of not actually using PRP. Let’s…read more

An Update on RCTs for Knee Osteoarthrtitis

Two years ago, I summarized all of the RCTs for PRP used to treat knee arthritis. It’s now time for an update, especially with the recent craziness around fake PRP studies. Let’s dig in. What Is an RCT? The top level of research quality is called an RCT or Randomized Controlled Trial. Usually, two treatments…read more

A Tale of Five Knee Joint Injections: You Get What You Pay For

It’s always hard to explain to patients how training and expertise in medicine vary widely. The good news is that in the more established areas of medicine represented by board certification, while the skill levels between doctors are different, there is a minimum standard of competency. However, once one gets into Regenerative Medicine where no…read more

Does Curcumin Work to Treat Knee Osteoarthritis?

Academic medicine has had a strange relationship with supplements. Many times, after many years of screaming at the rain about supplements, they have to admit that one or another may actually work. That’s what’s happening now with the Indian spice Curcumin. Let’s dig in. What Is Curcumin? Anyone who has eaten Indian food knows Curcumin.…read more

Do You Have PRP Derangement Syndrome (PDS)?

I’ve documented through the years that while some forward-thinking orthopedic surgeons have embraced using PRP, many have an irrational disdain for it. This is such a bizarre juxtaposition of the evidence that I call this PDS (PRP Derangement Syndrome). Today we’ll review a recent study that proves this point. Let’s dig in. What is PRP?…read more