Bone Marrow Concentrate

Bone marrow concentrate (or “Concentrated Bone Marrow” or “Bone Marrow Aspirate Concentrate” or “BMAC”), is a concentrated form of autologous bone marrow. Bone marrow concentrate is the result of centrifuging bone marrow to obtain a smaller volume which is more highly concentrated with cells and growth factors and therefore more useful as an injectate.

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What Are the Intertransverse Ligaments?

As I have said many times, ligaments are the red-headed stepchild of the spine. Meaning they are often ignored by 99% of the physicians treating spine problems. However, they are important and ubiquitous throughout the spine. Today we’ll review the Intertransverse ligaments, what they do, and why they could be causing you problems. Let’s dig…read more

What Does the Length of Recovery after Orthobiologics Say About Your Condition?

One of the things that is critical to understand for any patient getting an Orthobiologic procedure is how fast you recover usually tells us something about your medical condition. In particular, patients that enter into a prolonged recovery may have more issues that spell trouble long-term. Hence, let’s dive into that issue this morning. The…read more

The Bench Scientist False Dilemma

Credit: Shutterstock I’ve blogged a few times about the widening rift between a handful of media-savvy bench scientists and physicians who use regenerative medicine techniques to help patients avoid invasive orthopedic surgery. This past few weeks we’ve seen several unscientific things in the news and in bench science blogs about PRP and Bone Marrow Concentrate.…read more

How Many Patients Get PRP vs. BMC?

A big question I get from patients is should I get PRP or a Bone Marrow Concentrate procedure? This morning we’ll go over data from our treatment registry that shows what tens of thousands of patients have gotten since 2005. Let’s dig in. PRP vs BMC PRP stands for platelet-rich plasma. That’s concentrated blood platelets…read more

How Does Orthopedic Surgery Stack Up to Interventional Orthopedics?

As I have shown a few times, orthopedic surgery has an embarrassingly poor evidence base. I recently covered a new study that helped confirm this issue a few weeks ago and I have since performed a deep dive to compare how Interventional Orthopedics stacks up. Let’s dive in. The Old Gaurd versus the New Kid…read more

Why Are Knee Bone Marrow Lesions A Big Deal?

What is a bone marrow lesion? If you have knee arthritis, why should you care? Today we’ll dig into why these are a big deal through the story of a basketball player’s knee. What Is a Bone Marrow Lesion? Many think that a joint like the knee has two main parts – the bone and…read more

2021 All Stem Cell Infographic

I’ve been blogging a bit less lately due to the hours and hours that these two annual stem cell research infographics have consumed. This morning I’m finally done with the all cell types document which has some new surprises. Let’s dig in. What Are These Infographics? These are documents I produce every year (except last…read more

2021 Bone Marrow Research Infographic

Every year, I spend a number of hours searching the published medical literature for various new publications in orthobiologics and cell therapy. I produce two infographics, one focused on bone marrow cells and the other on all cell types. This is the 2021 edition of the bone marrow infographic. (Click here to view larger) What…read more
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