Orthobiologics

Fluoroscopy vs Ultrasound for Orthobiologic Spine Procedures

One of the more interesting debates from the past 5 years has been the use of fluoroscopy versus ultrasound guidance in advanced spinal injections. This one gets physicians emotional, as many believe that they can now offer patients the same type of injections using only an ultrasound machine when compared to x-ray guidance. So let’s…read more

A Mess of a BMA Study Can Teach Us About Orthobiologic Research

One of the hallmarks of good science is trying to limit variables. That’s what makes clinical research so hard, as making sure that there are only one or two differences between one group of patients and another isn’t always easy. That gets less complex when you’re measuring the lab metrics of something like a bone…read more

VittiLabs, the Sopranos, and an FDA Warning Letter

I’ve blogged quite a bit on the crumbling amniotic and umbilical cord fake stem cell market. Despite peer-reviewed research demonstrating that these products clearly have no stem cells, throughout social media, we still see patients who are getting bombarded by influencers who claim they are loaded with young and vital stem cells. One of the…read more

Does Testosterone Help Orthobiologic Procedures?

The same patient who asked the question about PRP vs BMC and ligament healing yesterday also asked about whether taking testosterone could help with healing after an orthobiologic procedure. That same prolotherapy physician who launched the last blog had also claimed that there was no doubt that the science showed that testosterone supplementation helped his…read more

CFU-f 101: To Be an Orthobiologics Expert You MUST Learn This

The blind leading the blind is one of my favorite expressions. As one of the founders of this field of interventional orthobiologics, the fact that this statement applies to much of our existing orthobiologics education is concerning to me. Nowhere is this more true than the concept of stem cell dose and CFU-f assays. Hence,…read more

More Research on How Bone Marrow Is Collected Is Critical

Any expert in any field can easily pull back the curtain on how the sausages in that field are made. What I mean is that any field sufficiently complex to need experts has a huge number of variables that determine the quality of the end product. The same rules apply to interventional orthobiologics. There are…read more

Why Concentration Matters in Orthobiologics: My Recent TOBI Presentation

Dose is a critical concept in medicine. In fact, a doctor who doesn’t know the dose of medication he injects into your body would lose a medical license. However, for far too long, we’ve allowed physicians practicing orthobiologic procedures to inject these products without knowing the dose. Our recent research and papers published by others…read more

What Does Treating Hip AVN without Surgery Have to Do with the History of Orthobiologics?

Many of the advanced interventional orthobiologics procedures currently used in peripheral joints and spine were developed by our Colorado HQ. That led to the creation of the Interventional Orthobiologics Foundation (IOF) which has continued to teach and evolve these breakthrough procedures. However, one procedure that we didn’t develop is the precise x-ray-guided injection of bone…read more