Research

More Research on How Bone Marrow Is Collected Is Critical

Any expert in any field can easily pull back the curtain on how the sausages in that field are made. What I mean is that any field sufficiently complex to need experts has a huge number of variables that determine the quality of the end product. The same rules apply to interventional orthobiologics. There are…read more

Want to Live Longer? New Research Says Do These Simple Things…

Given the hundreds of billions spent every year on supplements and various “anti-aging” treatments we’re all fighting father time. In a way, that’s also what I do at Regenexx, focus on how to keep aging musculoskeletal systems going without big, life-altering surgeries. However, are there some really simple things you can do to cheat death?…read more

Dr. Centeno Presented at TOBI this Weekend

I lecture around the country at various medical conferences every year. This weekend I was in Ft. Lauderdale, Florida sharing several new research studies from our research team at the TOBI orthobiologics conference. Let’s dig in. Basic Science in Orthobiologics Our lab research team works on several critical projects every year. In fact, as a…read more

New Lab Research Doesn’t Help Improve Prolotherapy

A colleague recently sent me a lab-based study that claims that the standard solution used for ligament and tendon prolotherapy should be lowered in concentration. Since that would be a big deal, I decided to take a deep dive into the study. What I found was that the study is not helpful in determining whether…read more

Tylenol and PRP: Is the Tylenogeddon Warranted?

This past few weeks, a new research article suggested that taking Tylenol with a PRP shot may be a bad thing. I’ve been a bit too busy this month to get into this as a blog topic, but with the craziness winding down, it’s time to review this new paper. Let’s dive in. Why Perform…read more

Mesenchymal Stem Cell Research Continues To Increase

Short blog this morning. I’ve posted many times about how the year-over-year research on mesenchymal stem cells (MSCs) continues to increase. At some point, I expected this to level off, but that hasn’t happened yet. Let’s dig in. What is a Mesenchymal Stem Cell? If you’ve had a bone marrow concentrate procedure, this is believed…read more

Bone Marrow Concentrate and Non-union Fractures

The good news is that fractures almost always heal in a few months, but the bad news is sometimes they don’t. When that happens, that’s called a “non-union” which can be a mess requiring additional surgery. However, we’ve known for decades that bone marrow concentrate has fracture healing capabilities. Let’s dig in. What Happens When…read more

New Day New Large PRP Saline Control Study: a Comparison to Bennell et al

What’s amazing is that every month now, we’re seeing new Platelet-Rich Plasma (PRP) studies coming out. A new one is interesting as it’s larger than the new JAMA study that was reported to be the “last word” on PRP and Knee Arthritis. So let’s dive into that comparison this morning. The Benell et al and…read more