Another Study Shows the Superiority of Bone Marrow as a Source for Stem Cells used in Cartilage Repair

By /

Yet another study that shows that bone marrow derived cells are more cartilage produicing than adipose (fat) derived stem cells. This study also showed bone marrow cells were better than those obtained from periosteum (covering of a bone), synovium (the lining of a joint), adipose (fat), and muscle. The authors concluded: “The bone-marrow-MSCs produced much more cartilage matrix than that of other groups. Gross and histological grading scale indicates that the defects repaired by MSCs isolated from bone marrow are superior to that repaired by MSCs isolated from periosteum, synovium, adipose tissue, and muscle (p < 0.05).” We’re not wed to one stem cell source, but try to match the source of stem cells to the patient’s problem. For example, we’ve noted that adipose tissue is great for a structural graft that happens to contain stem cells (for example to buttress a failing knee meniscus). Bone marrow stem cells are best to help joints heal or areas where you need to establish new blood supply. Finally, blood derived stem cells work great for things like rotator cuff repair, meniscus tears, ligament/tenson injuries, etc... Again, having lot’s of tools in the tool box always benefits the patient more than only having one!

Join us for a free Regenexx webinar.

If you have questions or comments about this blog post, please email us at [email protected]

NOTE: This blog post provides general information to help the reader better understand regenerative medicine, musculoskeletal health, and related subjects. All content provided in this blog, website, or any linked materials, including text, graphics, images, patient profiles, outcomes, and information, are not intended and should not be considered or used as a substitute for medical advice, diagnosis, or treatment. Please always consult with a professional and certified healthcare provider to discuss if a treatment is right for you.

Get Blog Updates by Email

By submitting the form, you are agreeing that you read and consent to our Privacy Policy. We may also contact you via email, phone, and other electronic means to communicate information about our products and services. We do not sell, or share your information to third party vendors.

Copyright © Regenexx 2021. All rights reserved.



9035 Wadsworth Pkwy #1000
Westminster, CO 80021


*DISCLAIMER: Like all medical procedures, Regenexx® Procedures have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.

Providers listed on the Regenexx website are for informational purposes only and are not a recommendation from Regenexx for a specific provider or a guarantee of the outcome of any treatment you receive.