Comparing the Number of Cells in Regenexx Procedures to the Rest…

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regenexx vs other system comparison

You may not know that when it comes to living stem cell procedures that almost all doctors use simple bedside machines. So this morning I’ll educate you on that process and compare the number of cells we use in our stem cell procedures to everyone else. Let’s dive in.

What is a Living Stem Cell Procedure?

Regrettably, most of what you can find today that’s advertised as “stem cells” is a scam. Meaning it’s birth tissue derived from either amniotic or umbilical cords and contains no living stem cells. However, if you want to get a living stem cell therapy, there are really only two options, using your fat or bone marrow. As far as fat is concerned, to get the stem cells out, you need to digest it. That’s illegal per current FDA guidelines. Hence, that leaves your bone marrow as the sole source of a living stem cell therapy that’s FDA compliant.

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What You Should Expect From a Bone Marrow Stem Cell Procedure?

First, the doctor performs a bone marrow aspirate. This involves numbing the area by placing a needle into the bone to pull out what looks like thick blood. This is a very critical step of the procedure to maximize the number of stem cells you receive, but regrettably, most doctors don’t do this part well, so they short change their patients.

Where this marrow aspirate comes from matters. For example, many orthopedic surgeons take aspirate from the knee. While this is convenient for the surgeon performing a knee surgery, this shortchanges the patient because this source has fewer stem cells than the pelvis. So a good bone marrow draw usually starts in the back of the hip area.

The next part of the procedure where most physicians place their convenience over what’s best for the patient is the bone marrow draw technique. Most physicians will merely place the needle into the area and draw as much as they can as quickly as they can. The problem? This drastically reduces the number of stem cells available for the therapy. Instead, in order to maximize the number of cells, the doctor should be taking small amounts from many areas.

As a concrete example, yesterday we had a visiting physician who observed two of my bone marrow aspiration procedures. He was clearly surprised by how many sites I drew from on each side. So as I show you the graphs comparing the number of cells in a Regenexx procedure to the bedside machines on the market, realize that beginning with a good draw is the first step in producing the most cells possible per treatment.

The Bedside Centrifuge Problem

Most physicians doing this work use a bedside centrifuge. This is a simple machine that sits someplace in the office that has a plastic kit where the bone marrow goes. So all the doctor or his assistant knows is where that kit goes in the machine and where the “On” button lives. The machine then does what it does and then produces what it produces.

The problem with this set-up, as you’ll see from the cellular numbers below, is that it’s very inefficient at concentrating bone marrow cells. This is why we have always used a much more expensive and resource intensive on-site lab to do this work. In addition, the bedside machines all leave out parts of the bone marrow that contain stem cells, which gets thrown away by the doctor.

How Does Regenexx Stack Up?

Below is a graph showing the number of cells in the final bone marrow concentrate product once it’s been processed. For the common bedside machines on the market we used their published numbers:

regenexx vs other machines

The height of the bars here equals the number of cells per cc delivered. As you can see, the Regenexx bone marrow processing delivers substantially increased numbers.

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Knowing the Dose

First, you’ll note that the number of patients that made up this data for Regenexx is 578 whereas the other companies only report 20-40 patient samples. This glaring difference highlights another contrast to what we do. Not that our data has almost 600 samples. Why? We count the cells in every sample for dosing purposes, so this data comes out of the Centeno-Schultz processing lab. The other companies have no ability to count cells, so their data came out of some lab where they sent a few samples for research purposes.

Knowing the dose of what it is you’re injecting is key. At Regenexx we count that cell dose and have dosing guidelines. Doctors who use these machines have no idea how many cells they’re delivering. For example, do they have enough cells to inject both knees? They have no idea.

How Can Regenexx Deliver Better Numbers?

How can Regenexx get these high cell numbers? First, our draw technique is very different than the average doctor. So we’re starting with many more cells than the companies that produced these white papers on their products. In addition, as I said, the problem with bedside machines is that they can’t get rid of the non-cellular portions of the bone marrow at any reasonable level of efficiency. In addition, on the other side of that calculus, they throw away key parts of the marrow that contain cells. Finally, these machines are one size fits all, whereas our processing protocols for our labs are designed to fit the processing to the unique patient sample.

The upshot? As you can see, we deliver far more cells at Regenexx than the vast majority of providers out there. While that doesn’t always guarantee a result, based on the published literature, it improves your chances of success.

If you have questions or comments about this blog post, please email us at [email protected]

NOTE: This blog post provides general information to help the reader better understand regenerative medicine, musculoskeletal health, and related subjects. All content provided in this blog, website, or any linked materials, including text, graphics, images, patient profiles, outcomes, and information, are not intended and should not be considered or used as a substitute for medical advice, diagnosis, or treatment. Please always consult with a professional and certified healthcare provider to discuss if a treatment is right for you.

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