The Interventional Orthobiologics Blog

Blog covering topics and research in interventional orthobiologics, interventional orthopedics, and orthopedic procedures.

Blogging From the Caymans Again…

Here I am again, as I am three times a year, down in beautiful Grand Cayman. Why? Because the licensed culture expansion site here allows me to use more advanced stem cell care in some of my patients. PRP vs. Stem Cells About 90% of what I prescribe for the patients I see is a…read more

Regenexx Corporate Continues It’s Rapid Growth

Regenexx has been on a tear lately, adding many new companies and insurance brokers to our corporate plan. In the meantime, we’re disrupting a powerful cabal in health insurance and healthcare, so it’s also been interesting to see the blowback. The most recent pushback came yesterday from a local hometown newspaper, the Des Moines Register.…read more

Tramadol Plus an Antidepressant is Bad News…

A very common medication combo prescribed to patients with chronic pain is tramadol (Ultram) plus an antidepressant.  However, new research may call into question whether this is a good idea. Let’s dig in. Depression and Pain One of the biggest chicken and egg controversies that has been zinging around in chronic pain treatment circles for…read more

Does Your Gut Bacteria Impact Physical Performance?

There is nothing that has upended a greater swath of medicine these past few years than studies on the microbiome. We’ve seen everything from your weight to depression tied to the bacteria in your gut. Now a new study again blows my mind by linking a type of bacteria in the gut to athletic performance?…read more

Do Bench Scientists Have an Ethical Duty to Report That Their Point of View Is Not the Only One?

I’m seeing an interesting change in the dialog around the stem cell wild west. One that is so juxtaposed to reality, it brings up all sorts of ethical problems. What could that be? Bench scientists from one side of campus providing quotes for news stories against the use of orthobiologics while on the other side…read more

Do Your Stem Cells Differentiate and Stick Around?

One of the biggest debates right now in regenerative medicine is whether stem cells act through differentiation or a paracrine effect. If you’re considering a stem cell treatment, knowing what all that means is important. Let me explain. Differentiation vs. Paracrine The type of stem cells being most often to treat orthopedic conditions are mesenchymal…read more