The Interventional Orthobiologics Blog

Blog covering topics and research in interventional orthobiologics, interventional orthopedics, and orthopedic procedures.

How to Avoid Discography Side Effects: Biologic Discography

Frankly, until we became the first in the world to inject stem cells into discs, discography never made much sense to me. I would tell patients, “I’m going to poke a hole in your disc to see if there’s a hole in your disc.” However, when we began to see that platelet rich plasma and…read more

A Big Fat Blow for the Stem Cell Literature: Major Paper Withdrawn

This past year, I was actually excited to add fat stem cells to my big annual review of the orthopedic stem cell literature. While a few small papers had been published, a big part of that literature was a huge data set by Michalek out of Eastern Europe, which purported to show that fat stem…read more

Does Hypertension Increase Your Risk for Knee Arthritis?

If you have high blood pressure, does that increase your knee arthritis risk? Are the two merely related, or is there something about hypertension or its causes that creates arthritis? Knee Osteoarthritis and Hypertension Knee osteoarthritis (OA) affects the smooth and tough connective tissue in the knee called cartilage. When that cartilage begins to break…read more

Does Age Affect Stem Cell Treatment Success?

Does your age impact stem cell treatment success? We’ve looked long and hard through the years for this association, but it’s been, for the most part, elusive. We’ve published a number of scientific papers on the topic, but now a group of chiropractors is fabricating from thin air a narrative about age and stem cells.…read more

FDA Crackdown on the Stem Cell Wild West

This week, the FDA announced that it was sending a warning letter to US Stem Cell in Florida and a California venture known as Stem Immune, linked to the Cell Surgical Network. What do both of these clinics have in common? They both use a product called stromal vascular fraction (SVF) obtained from fat. The…read more

Stem Cell Seminars: 7 Questions to Separate Real from Hype

There’s been an explosion in clinics offering stem cells for orthopedic treatments in the last few years. The most aggressive blanket major metro areas, taking out full-page ads on the front pages of major newspapers, putting on large stem cell seminars that double as high-pressure sales events. As a consumer, especially one making medical decisions…read more