The Interventional Orthobiologics Blog

Blog covering topics and research in interventional orthobiologics, interventional orthopedics, and orthopedic procedures.

How Stem Cells Work: Contact Inhibition or How to Stop Making Copies of Yourself

How Stem Cells Work – Part 6 Today’s installment of How Stem Cells Work sounds daunting, but is pretty simple. What is the big difference between the safety profile of adult stem cells (like the mesenchymal stem cells (MSCs) we use), embryonic stem cells, and the newer induced pluripotent stem cells (iPS)? The single topic that…read more

How Stem Cells Work: Differentiation or The Cellular Oedipus Complex

How Stem Cells Work – Part 2 This is the second in my short format video series on how stem cells work. Today I cover the most traditional mechanism described about how adult stem cells do their job in the body to maintain and repair tissue. Every trip to the gym involves cells that get damaged or…read more

Does Male Hormone Optimization with Testosterone Help Stem Cell Production?

About two years ago, I came across the web-site of a doctor who had just begun to use fat stem cells, mostly for cosmetic uses, but also dabbling in knee arthritis. He claimed that many research studies showed that testosterone and other age management remedies dramatically increased stem cell production and quality. I immediately went onto…read more

What Causes Shoulder Arthritis?

What causes shoulder arthritis? See that shoulder x-ray up there with that big bone spur in the bottom of the joint? That scares me. This past month or two, my shoulders have been aching. As a now 50 year old physician who loves to lift weights, maybe this shouldn’t be too surprising? However, I’ve also…read more

More on Zombie Stem Cells

A while back I blogged about the fact that living stem cells could be isolated from fresh cadavers up to 2+ weeks old. This is a bizarre thing and testament to how, even in a limited nutrient and oxygen environment, these hearty cells keep going. In fact, it may be because many stem cells live in…read more

Does Low Vitamin D Cause Neck Disc Herniations?

Vitamin-D has been a very big deal this past few years. There’s been back and forth on whether low vitamin-D is associated with arthritis. However, can low levels also cause neck and back problems? On the heels of this controversy, there was an interesting study this past month on an association between low vitamin D…read more