Knee Surgery Alternative At Pain Doctors Medical
Regenerative medicine treatments may offer a superior alternative to knee surgery or knee replacement.
Procedures using Regenexx injectates may provide a non-surgical option for individuals experiencing knee discomfort related to arthritis or injury. Physicians in the licensed Regenexx network perform customized treatments designed to support the body’s natural healing process.
Regenexx platelet-rich plasma (PRP) and bone marrow concentrate (BMC) injectates, which use the individual’s own healing agents, are utilized to address common orthopedic conditions such as meniscus injuries, ACL strains or tears, and knee osteoarthritis. These procedures aim to help reduce pain and may improve mobility, potentially helping patients avoid or delay the need for knee surgery.
To determine whether this approach may be appropriate for a condition, a physician will assess medical history, imaging, and treatment goals.
Are You a Regenexx Candidate?This location is for evaluation appointments only.
- Knee
- Osteoarthritis
- Meniscus
- ACL
The Regenexx® Alternative to Knee Surgery and Knee Replacement Surgery
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For individuals managing knee discomfort, interventional orthobiologics may offer a non-surgical alternative to steroid knee injections or invasive surgery. This approach uses the body’s own healing agents to support tissue repair and may help reduce pain associated with knee injuries and arthritis.
Recent research suggests that some common orthopedic knee surgeries, including meniscectomies, may provide no greater benefit than placebo or sham procedures. Knee replacement surgery is a significant intervention with associated risks . Even when successful, surgery typically requires months of rehabilitation to regain mobility and strength . In some cases, surgery can worsen the original issue by potentially accelerating joint degeneration and contributing to osteoarthritis.
The Regenexx approach at Pain Doctors Medical may help patients with knee injuries or degenerative conditions. This method, known as Interventional Orthopedics, uses advanced image guidance (fluoroscopy and ultrasound) to deliver concentrated doses of the body’s own cells directly into targeted joint structures. These biologic materials are placed precisely at the site of concern to support repair processes, which rely on accurate placement.
Procedures utilizing proprietary Regenexx processing methods in Perth Amboy, New Jersey may help improve knee function and may help reduce discomfort without surgery. In this outpatient setting, physicians in the licensed Regenexx network use image guidance to inject customized concentrations of the individual’s own healing agents into specific areas of damage to may stabilize and support the knee joint. This technique requires advanced training and adherence to Regenexx protocols, and cannot be replicated by providers without Regenexx certification.
Get back to the activities you enjoy without knee surgery
Patients may experience knee symptoms that include sudden catching, locking, or giving way, sometimes leading to falls or instability. These patterns of joint discomfort and mechanical symptoms can occur repeatedly, causing patients to hesitate when considering traditional treatment options, such as surgery or joint replacement.
This is a common concern among individuals with knee issues. Physicians in the licensed Regenexx network at Pain Doctors Medical may help patients better understand their condition and explore appropriate next steps.
Imagine walking across the park, following your toddler grandchild or walking your dog, when your knee catches and then buckles. You fall to the ground, stricken by severe intense knee pain, not knowing what to do, unable to get up and put weight on your leg. You feel helpless, as your grandchild or dog are depending on you to keep them safe.
This has been happening off and on for months, with your knee locking alternating with giving way. You’ve been too afraid to visit the doctor because you feel too young to be faced with knee replacement or surgery that’s going to make you feel old. It happened to your parents, and you don’t want it to happen to you. And they spent a lot of money on procedures that didn’t work. Where do you turn?
We understand. We want to help you make sense of how the body works, how you’re not broken beyond repair, how to find the right help for you, and what your next steps are to getting that help.
What are some common causes of knee pain?
Knee pain can arise from a variety of conditions, including:
- Fractures or dislocations of the knee
- Ligament injuries, such as ACL or PCL tears
- Cartilage damage, including meniscus tears
- Bursitis (inflammation of the fluid-filled sacs)
- Tendonitis or tendon tears
- General knee discomfort related to factors like poor footwear, iliotibial band syndrome, or hip misalignment
- Osteoarthritis or other degenerative changes in the joint
Understanding the structure of the knee can provide helpful context for these causes.
Knee Anatomy

The knee is a complex joint composed of bones, cartilage, ligaments, tendons, and fluid-filled sacs, all working together to support movements such as walking, running, jumping, and squatting.
Bones
The knee is formed by the femur (thighbone), tibia (shinbone), and patella (kneecap). The ends of the femur and tibia meet at rounded areas called condyles. The medial condyle is on the inner side of the knee, while the lateral condyle is on the outer side.

Cartilage
The meniscus is a key cartilage structure in the knee, located between the condyles of the femur and tibia. Each knee has two menisci—medial (inner) and lateral (outer). The meniscus helps distribute body weight, absorb impact, reduce friction, and protect the smooth cartilage covering the ends of the bones. Degenerative changes to this cartilage, such as in osteoarthritis, are common causes of chronic knee pain.
Bursa Sacs
Fluid-filled sacs called bursae cushion pressure points between bones and tendons, reducing friction during movement and protecting the joint from constant rubbing.
Ligaments
Ligaments are strong connective tissues that stabilize the knee by connecting bones. Key ligaments include the anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL), which maintain alignment between the tibia and femur and support overall knee stability.
Tendons
Tendons connect muscles to bones and facilitate movement. The quadriceps tendon links the quadriceps muscle to the patella, while the patellar tendon connects the patella to the tibia. Tendons, together with surrounding muscles, are essential for enabling controlled knee motion.
Treatment Options for Knee Pain from Injury or Arthritis
What can I do to reduce knee pain from injury?
In order to relieve knee pain, we have to figure out what’s causing the knee pain. As you can see, the knee has a lot of parts that keep it protected, stable, and mobile. Any one of these can be the cause of knee pain. In addition, pain can be originating outside of the knee joint but still causing knee pain, in the case of iliotibial band (ITB) syndrome or poorly fitting or worn-out shoes.
Some knee conditions require rest and/or special exercises prescribed by a physical therapist. Yet, some require advanced medical attention simply because the pain is not being relieved or the function is not improving. Be careful about immediately accepting advice to undergo surgery. Research has shown that many of the most common surgeries, such as a “knee clean up”, are largely ineffective and unnecessary, leaving the patient in worse shape in the long term. Regenexx doctors are highly trained in diagnosing and treating knee issues non-surgically. In some cases, surgery may be the best solution.
To effectively reduce knee discomfort, a thorough evaluation is necessary to identify the root cause. The knee’s complex structure, which includes bones, cartilage, ligaments, and tendons, is critical for protection, stability, and mobility. Damage to any of these parts can lead to discomfort. Furthermore, pain may originate outside the joint, such as in the case of iliotibial band (ITB) syndrome or due to poorly fitting or worn footwear.
Some knee conditions necessitate rest and/or specific exercises prescribed by a physical therapist. However, when discomfort is persistent or function fails to improve, advanced medical attention may be required. Patients should be cautious about immediately accepting advice to undergo surgery. Research has shown that many common surgical procedures, such as arthroscopic meniscectomies (“knee clean-ups”), may be ineffective for some individuals and could result in outcomes that do not meet expectations. While surgery may be the most appropriate solution in some severe cases, physicians in the licensed Regenexx network are trained in evaluating and addressing knee issues with non-surgical interventional orthobiologic options.
What does arthritis pain in the knee feel like?
Arthritis literally means inflammation of a joint . Osteoarthritis is a specific type of arthritis, often referred to as degenerative joint disease . While it can affect various joints, it most commonly damages the knees, hands, hips, and spine .
Knee osteoarthritis symptoms typically develop slowly and can worsen over time . Although the chances of developing arthritis may increase after 45 years of age, it can affect individuals at any age . Symptoms in the knee may include swelling and stiffness, as well as discomfort . There may also be associated cracking noises, and patients may experience feelings of weakness or “buckling” of the knee . Additionally, loose fragments in the joint from cartilage or other tissues can cause the knee to lock during movement. Both buckling and locking of the knee may increase the likelihood of falls or further joint stress .
Discomfort and swelling in the knee can be worse in the mornings or after prolonged periods of sitting, and pain may increase during rainy or humid weather .
What can I do to reduce arthritis pain in my knee?
Reducing discomfort from chronic conditions like knee arthritis often involves a similar initial approach to acute injuries, but the duration of the condition requires a long-term perspective .
Arthritis in the knee is typically caused by constant, uneven, undue wear within the joint without the proper environment or space for healing.
While pharmaceutical options exist to mask discomfort symptoms, these are associated with potential side effects that can contribute to or worsen other medical conditions. An alternative approach is to address the uneven wear and provide the necessary environment to may support the body’s natural ability to heal.
For many, surgery, in the form of joint replacement, may be an option for knee arthritis relief. However, this is a serious intervention that may be avoidable for some individuals through the Regenexx approach, which includes interventional orthobiologic procedures using Regenexx injectates designed to support the body’s natural healing response.
Physicians in the licensed Regenexx network may be able to assist patients in exploring these non-surgical alternatives. You can consult with a physician in the licensed Regenexx network at Pain Doctors Medical, 75 Smith Street, Perth Amboy, New Jersey.
How to promote knee joint health?
The human body possesses natural repair mechanisms that are constantly engaged. A simple example is the healing that occurs after a minor injury, where specialized cells are dispatched to seal and repair damaged tissue.
Similarly, the body conducts ongoing maintenance to support function and recovery. These processes, while not always visible, play a vital role in tissue repair throughout the body, including within the knee joint.
Several factors may influence an individual’s ability to recover from damage and maintain joint health. These lifestyle factors may include:
- Smoking status
- Alcohol consumption levels
- Quality and quantity of sleep
- Frequency and intensity of physical activity
- Nutrition and digestive function, which affect how nutrients reach the body’s cells
- The body’s response to stress
These lifestyle factors can influence how well the body recovers from acute injuries and long-term changes, such as those that contribute to knee arthritis. Even when these factors are optimized, there may still be instances when the body benefits from additional support.
What is interventional orthobiologics? How can this approach help manage knee pain?
Many typical medical treatments rely on medications that mask discomfort without addressing the underlying issue. In some cases, surgical options are pursued that may not result in meaningful long-term improvements in function or discomfort.
Surgical procedures can be physically demanding and involve significant recovery time. Healing from such interventions, particularly joint reconstruction, can require months or more of rehabilitation to regain range of motion, strength, and balance. The joint may not always return to optimal function. Joint replacement introduces foreign materials into the body, which may trigger an inflammatory response. While surgery may be appropriate in certain severe cases, it is a significant step and may not always be necessary as an initial treatment.
The Regenexx approach may support the body’s natural repair mechanisms by directing concentrated cellular elements to the site of joint damage. This process does not involve synthetic materials or pharmaceuticals but instead uses the individual’s own biological material, prepared using proprietary Regenexx processing methods, and precisely applies it to the affected area.
This specialized field is referred to as interventional orthobiologics. Procedures using Regenexx injectates have been used to support improved joint function, mobility, and reduced discomfort, while potentially helping individuals avoid surgery.
Physicians in the licensed Regenexx network are among the most experienced in using this non-surgical approach to orthopedic care. Patients can complete the Candidate Form to learn if this approach may be appropriate for their condition.
For a consultation with a physician in the licensed Regenexx network, patients may visit Pain Doctors Medical, 75 Smith Street, Perth Amboy, New Jersey.
Find a Location
Find a physician in licensed Regenexx network.
Regenexx Benefits
- Increased function
- Pain reduction
- Most individuals do not experience extensive downtime
- Minimal time off of work
- No surgery
- Minimal use of mobility tools (crutches, etc.)
- Minimal disruption of regular routine
75 Smith Street
Perth Amboy, NJ 08861
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