The Interventional Orthobiologics Blog
Blog covering topics and research in interventional orthobiologics, interventional orthopedics, and orthopedic procedures.
Back Pain Won’t Stop? Multifidus Research Update
Most patients don’t realize that if their back pain won’t stop that there’s usually a simple reason that’s invisible to their doctor. In addition, it’s hiding in plain sight on their MRI images, it’s just that nobody with a firm knowledge of the research on chronic low back pain has ever looked. This finding is called…read more
Did the Mesoblast Degenerative Disc Disease Trial Succeed or Fail?
This past week Mesoblast, a company pursuing the business model of selling someone else’s mass produced stem cells in a vial, launched a major PR campaign to announce their phase III FDA disc degeneration trial. From reading the press releases, you would think that the phase 2 trial showed pure magic. I had reviewed the results…read more
How Much Human Stem Cell Research is There?
(Click here for a larger view) Every year or so I summarize all of the human bone marrow mesenchymal stem cell research in orthopedics. At first this exercise began to answer the simple question of how much research do we have using real patients? Is it a lot or a little? After all, many in…read more
Exercise Changes Growth Factors in Platelets
Love it or hate it, exercise seems to be one of the areas where we can make the most significant impact on our health. We know exercising and keeping our weight under control have a lot to do with the chemical environment within our joints, but can exercise impact the makeup of the PRP made from our…read more
ACL Surgery Failure: Can You Heal a Torn ACL Graft with Stem Cells?
We’ve been treating torn ACL ligaments for years without the need for surgery. An interesting problem is ACL surgery failure, or in other words the patient who has already had surgery and then tears the surgical graft. Can a super precise stem cell injection under advanced imaging guidance help these tears? This is the story…read more
Stem Cells and Bone on Bone Arthritis
I often get asked about stem cells and bone on bone arthritis, i.e. can a stem cell injection help patients with severe knee arthritis? After all, surgeons often use the term “bone on bone” to describe these patients, a situation that sounds frightening. Jim from Pittsburgh was one of those patients, a hard working business owner…read more 