Platelet Rich Plasma

I’ve Returned and So Apparently Are the Neck Multifidus Muscles after Exercise!

I’ve been out for six weeks sailing the Med. It was another great trip and a much-needed break for an old guy! Today, let’s cover a new study that shows that cervical multifidus muscle atrophy can be recovered with exercise. Getting Back If you recall, we are on a four-year journey to sail the Mediterranean,…read more

Exosomes (Extracellular Vesicles) vs. PRP Used for Treating Orthopedic Problems

A few patients have been asking about using exosomes or extra-cellular vesicles to treat their aches and pains. As an expert in this space, knowing what I know about the research, this request doesn’t make sense. Hence, I wanted to educate everybody about this issue today. Let’s dig in. Facebook Hype Abounds The exosome hype…read more

Is PRP a DMOAD? The Influence of Platelet Concentration on Study Failure

The holy grail of osteoarthritis research has long been a Disease Modifying OsteoArthritis Drug or DMOAD. This is a medication you can take or inject that would slow or prevent the onset of wear and tear arthritis. A big question for doctors who have observed the power of orthobiologics is whether PRP is a DMOAD.…read more

How Do We Get Coverage for Orthobiologics? The Problem With Assigning Success Rates to Specific Orthopedic Surgeries

How has Regenexx been able to get more than a thousand US employers to cover interventional orthobiologic (IO) procedures? One of the ways is to perform analyses of how IO procedures can help their employees avoid surgery, save them money, and reduce their time out of work. Today we’ll explore just one little piece of…read more

Kratom and Interventional Orthobiologics Procedures

As you know, I often write about what I experience seeing patients. While Kratom has been on the periphery of my consciousness like it probably has been for many physicians, this past week, it was thrust to the forefront. This “drug” sold in gas stations and online turns out to be a potent opioid receptor…read more

2023 PRP RCT Infographic and Study Failure Analysis

Almost every year, I try to spend significant time diving into the literature on interventional orthobiologics and summarizing it. This helps me understand where we are in the evolution of the literature and hopefully provides some insight into what’s working and what’s not. This year I summarized the entire published literature on PRP injections for…read more

Disc Injections With Platelet Raisins and Protein Syrup

The last blog I published was on the mounting evidence for using PRP to treat the common causes of spinal pain. However, in that literature review, one study stood out. That research was abruptly halted at eight weeks, which was curious. As I sat down to read and analyze this paper in more detail, it…read more

Is There Solid Research on Using PRP to Treat Spinal Pain?

Art: Credit Dall-E with the prompt: “A human spine in 3D surrounded by red blood cells in the style of impressionism.” As you know, I often write about what I experience. This week an interventional spine physician questioned whether PRP would be useful in the treatment of lumbar radiculopathy or painful facet joints in the…read more