The Interventional Orthobiologics Blog

Blog covering topics and research in interventional orthobiologics, interventional orthopedics, and orthopedic procedures.

Hip Replacement or Back Fusion First? Timing Matters When Considering Risks

One of the clinical scenarios where bone marrow concentrate doesn’t work well is severe hip arthritis. In these cases, we often tell patients to get a hip replacement. However, it’s critical to understand that the body is connected, so for example, getting a back fusion may impact your hip replacement. Before I share the newest…read more

Drug Development vs. Physician Innovation: A Primer for Academics and Journalists

One of the things that really confuses bench scientists and science journalists is the stark difference between how drugs and medical procedures are developed and tested. These groups tend to conflate the two, which is like comparing apples and oranges and then being upset that a Vermont McIntosh is not like a California Tangerine. Let…read more

Does Knee Arthritis Severity Impact Stem Cell Treatment Outcome?

For so many therapies used to treat knee arthritis, the best way to determine if a specific therapy will help is the severity of the disease. Meaning that less severe knee arthritis responds better than the more severe forms of the disease. However, one of the things we’ve observed about our same day bone marrow…read more

Can the Organelles in Our Cells Get Injured? Mitochondrial Rescue

You know that your body has organs and that these can be injured by trauma. But did you know that your cells have organs that can be damaged the same way? Today I’ll review a new field of stem cell biology that may well form the basis for why some of our existing treatments work…read more

Is ACL Surgery a Second Hit to the Joint Cartilage?

I’ve blogged before on the idea that we now have high-level evidence that suggests ACL surgery itself is harming the joint. While at the Havemeyer Symposium (think tank) at CSU, one of the physician-scientists presented an interesting slide that supports this idea. Let me explain. The Prior Research As I have reported previously, data from…read more

What’s the Difference Between PRP and Platelet Lysate?

In this article: What are platelets? Platelet-rich plasma (PRP) Platelet lysate PRP vs platelet lysate One of the reasons I blog is to make sure that almost every possible question a patient could ask is covered by a detailed answer. This week a patient commented on one of my old YouTube videos on platelet lysate,…read more