When the Regenexx Procedure Doesn’t Work…

By Chris Centeno, MD /

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when the regenexx procedure doesn't work

This past week or so I’ve highlighted some great success stories and long-term results. However, every medical procedure known to man has a success and failure rate. This is why we routinely publish outcome data which contains the average of patients who did well, those that did OK, and those where the procedure was ineffective. This morning I’d like to highlight a patient who was treated down in Grand Cayman who got no meaningful results. Why post about when the Regenexx Procedure doesn’t work?  Because it provides patients the balance they need to decide if Regenexx is right for them.

First, I’ve blogged on other treatment failures many times in the past (see here, here, and here). This morning’s patient AB is a middle aged man with a history of four prior knee surgeries. While he had a metabolic syndrome (high blood pressure and prediabetes), the good news is that he had lost 35 pounds. His MRI showed almost full thickness loss of cartilage in the outside compartment of the knee, multiple areas of degeneration in what was left of his meniscus tissue (much of which had been removed in the prior surgeries) and his exam showed laxity in multiple important knee ligaments causing knee instability. The patient underwent a Regenexx-C cultured procedure back in January 2015 and recently he reported no positive results.

So what happened? Looking at our registry data on about 600 patients treated with this type of stem cell therapy, the severity of his arthritis doesn’t predict a bad outcome. Any stem cell therapy that uses the patient’s own cells is always only as good as the health of the cells. It’s certainly possible that the accumulated toll of the patient’s metabolic syndrome (high blood pressure and pre-diabetes) had reduced the activity and potency of his stem cells.

The upshot? No medical nor surgical procedure known to man works every time and our procedures are no different. We go out of our way to publish our results both online and in the peer reviewed scientific literature. These results contain all patient results that we have been able to obtain – which always includes patients who did well balanced by patients who had less of a response. Despite that transparency, it’s always best to post patient’s treatment failures to balance posting successes. While other clinics who treat arthritis patients don’t discuss treatment failures, since we’ve been doing this longer than anyone else, we feel the need to lead by example.

Chris Centeno, MD

Regenexx Founder

Chris Centeno, MD is a specialist in regenerative medicine and the new field of Interventional Orthopedics. Centeno pioneered orthopedic stem cell procedures in 2005 and is responsible for a large amount of the published research on stem cell use for orthopedic applications.
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Regenerative procedures are commonly used to treat musculoskelatal trauma, overuse injuries, and degenerative issues, including failed surgeries.
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Many Shoulder and Rotator Cuff injuries are good candidates for regenerative treatments. Before considering shoulder arthroscopy or shoulder replacement, consider an evaluation of your condition with a regenerative treatment specialist.

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Knees are the target of many common sports injuries. Sadly, they are also the target of a number of surgeries that research has frequently shown to be ineffective or minimally effective. Knee arthritis can also be a common cause for aging athletes to abandon the sports and activities they love. Regenerative procedures can be used to treat a wide range of knee injuries and conditions. They can even be used to reduce pain and delay knee replacement for more severe arthritis.

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Spine

Many spine injuries and degenerative conditions are good candidates for regenerative treatments and there are a number of studies showing promising results in treating a wide range of spine problems. Spine surgery should be a last resort for anyone, due to the cascade of negative effects it can have on the areas surrounding the surgery. And epidural steroid injections are problematic due to their long-term negative impact on bone density.

  • Herniated, Bulging, Protruding Discs
  • Degenerative Disc Disease
  • SI Joint Syndrome
  • Sciatica
  • Pinched Nerves and General Back Pain
  • And more
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Hand and wrist injuries and arthritis, carpal tunnel syndrome, and conditions relating to overuse of the thumb, are good candidates for regenerative treatments. Before considering surgery, consider an evaluation of your condition with a regenerative treatment specialist.
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Elbow

Most injuries of the elbow’s tendons and ligaments, as well as arthritis, can be treated non-surgically with regenerative procedures.

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Hip injuries and degenerative conditions become more common with age. Do to the nature of the joint, it’s not quite as easy to injure as a knee, but it can take a beating and pain often develops over time. Whether a hip condition is acute or degenerative, regenerative procedures can help reduce pain and may help heal injured tissue, without the complications of invasive surgical hip procedures.

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Foot & Ankle

Foot and ankle injuries are common in athletes. These injuries can often benefit from non-surgical regenerative treatments. Before considering surgery, consider an evaluation of your condition with a regenerative treatment specialist.
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*DISCLAIMER: Like all medical procedures, Regenexx® Procedures have a success and failure rate. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.

Providers listed on the Regenexx website are for informational purposes only and are not a recommendation from Regenexx for a specific provider or a guarantee of the outcome of any treatment you receive.