Interventional Orthobiologics

Interventional orthobiologics is a medical specialty that treats musculoskeletal conditions with image-guided injections of orthobiologics, including blood and bone marrow concentrate containing mesenchymal stem cells. This approach promotes healing and improves function, offering a non-surgical alternative to traditional orthopedic procedures. Regenexx customizes these treatments to individual needs, ensuring they are safe and compliant with regulatory standards.

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2024 Update on Interventional Orthobiologics Studies and Product Pipelines

Interventional orthobiologics research continues to advance at a furious pace. Last year, I published a blog that attempted to look ahead a bit at studies and products that may be available and posited a timeline for when that could happen. This year, I went deeper to search product studies/FDA trials and some key research studies…read more

Setting an Ethical Framework for Preventative Orthobiologics

Anyone practicing legit high-level Interventional Oorthobiologics (IO) has had the experience of a patient asking to have an area or body part treated just because that patient has some degenerative changes on imaging but no symptoms. As a field, I would argue that we are the first physicians in history to begin addressing this dilemma…read more

Upcoming Clinical Trials for Interventional Orthobiologics

Interventional orthobiologics is a field that’s gaining momentum every day. While legit players right now in the United States are sticking to things that are FDA compliant, like PRP, BMC, and MFat, several FDA clinical trials are winding their way through the system. This morning’s blog focuses on the ones I can find and invites…read more

Women in The Tour de France and Interventional Orthobiologics

Dr. Hyzy in our Regenexx HQ in Colorado recently got an email from an aging athlete who returned to ride the Tour de France after riding it in the 80s. I didn’t know much about the history of women in the Tour and this was an inspiring story, so I thought I would write about…read more

Rebutting Misinformation in Orthopedic Journals: Ittleman and Shapiro

Orthobiologic treatments represent a disruptive technology that I have blogged on dozens of times. Given that many patients who used to get invasive orthopedic surgery are now skipping those procedures and instead using interventional orthobiologics, orthopedic surgeons have varied reactions to this new playing field. We’ll explore those issues today in the context of an…read more

Analyzing CCI Procedure Failures: The SpaceX Approach

[The above video is a summary of this blog.] In any real medical procedure, there are always analyses of why patients fail to respond. This week I went through that process for a unique procedure I developed to help patients suffering from Craniocervical Instability (CCI). Let’s dig into that analysis and learn what it tells…read more

Why Aren’t Interventional Pain Management Physicians Offering More Regenerative Solutions?

These past few years I’ve seen that while regenerative medicine is gaining wider acceptance, there’s been an explosion in treatments being offered that aren’t nearly as elegant. What fits into that category and why does it make me uncomfortable? Let’s dig in. More Options are Better than Fewer The great thing about helping patients in…read more

Interventional Spine Physicians Finally Get the Memo on Bupivacaine

It would be hard for most people to believe that we’ve known for more than a decade that a long-acting anesthetic called Bupivacaine is toxic to cartilage and yet in interventional pain management, it’s still the most widely injected anesthetic into joints. Why that disconnect exists says much about the problems in modern medicine, but…read more
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