Regenerative medicine

Playing With Knee Steroid Data, Et Tu Harvard?

A few years back a seminal paper was published showing what many physicians knew was an issue, that mega-dose steroids destroy knee cartilage (1). However, this was a HUGE problem for many physicians who have been injecting this stuff with wild abandon for many years. Hence, it was only a matter of time before papers…read more

Can You Easily Determine MSC Content of BMC at the Bedside?

Dose is a key metric in medicine. However, dosing cells isn’t used in most of orthobiologics. However, is that about to change? Will it be possible to get a dose of stem cells at the bedside when using BMC or Mfat? Let’s dig in. Dose Matters Determining the stem cell content of Bone Marrow Concentrate…read more

Injecting the C1-C2 Facet Joint Under Ultrasound: A PA with a Scary Big Needle

I’ve been covering non-physician, mid-level providers performing all sorts of procedures for which, IMHO they lack adequate training. Some of these procedures are less risky than others, but this morning we’ll go over a physician’s assistant wielding a very big needle and sticking it into one of the highest-risk areas of the body. Let’s dig…read more

Umbilical Cord MSCs Sales 2.0: Using the Expanded Access Program?

You have read here many times about the fraudulent claims of umbilical cord tissue vendors that they are selling products with millions of young and vital mesenchymal stem cells. That was followed by the FDA crackdown last year and all seemed quiet for a while. However, now we’re seeing a new business plan emerge that…read more

Why You Might Want to Avoid Rotator Cuff Surgery

Earlier this month I presented the almost final data from our randomized controlled trial on shoulder rotator cuff tears at a large national conference on orthobiologics. The research will soon be submitted for publication, but you’ll get the first look at our data here. Let’s dig in. The Problem with Shoulder Rotator Cuff Tears and…read more

More Research on How Bone Marrow Is Collected Is Critical

Any expert in any field can easily pull back the curtain on how the sausages in that field are made. What I mean is that any field sufficiently complex to need experts has a huge number of variables that determine the quality of the end product. The same rules apply to interventional orthobiologics. There are…read more

Why Concentration Matters in Orthobiologics: My Recent TOBI Presentation

Dose is a critical concept in medicine. In fact, a doctor who doesn’t know the dose of medication he injects into your body would lose a medical license. However, for far too long, we’ve allowed physicians practicing orthobiologic procedures to inject these products without knowing the dose. Our recent research and papers published by others…read more

Regenexx Corporate Updates: 169,902 and 1,904

Regenexx is the world’s largest specialist-driven orthobiologics network. We’re also almost two decades old. The most exciting thing that’s happened in these past few years is that we continue to add more “corporate overage”. What’s that and why is that important? Let’s dive in. What is Regenexx? Regenexx is an invitation-only, specialist-driven medical network that…read more